B. Rockwell, C. Toth, W. Roach, D. J. Payne, R. Hopkins, P. Kennedy, D. Stolarski, G. Noojin, R. Thomas, C. Cain
{"title":"Retinal damage mechanisms and safety for ultrashort laser exposure","authors":"B. Rockwell, C. Toth, W. Roach, D. J. Payne, R. Hopkins, P. Kennedy, D. Stolarski, G. Noojin, R. Thomas, C. Cain","doi":"10.1117/12.349987","DOIUrl":null,"url":null,"abstract":"For the past several years the US Air Force has led a research effort to investigate the thresholds and mechanisms for retinal damage from ultrashort laser pulses [i.e. nanosecond (10-9 sec) to femtosecond (10-15 sec) pulse widths]. The goal was to expand the biological database into the ultrashort pulse regime and thus to allow establishment of maximum permissible exposure limits for these lasers. We review the progress made in determining trends in retial damage by ultrashort laser pulses in the visible and near infrared, including variations in spot size and number of pulses. We also discuss the most likely damage mechanisms operative in this pulse width regime and discuss relevance to laser safety.","PeriodicalId":8969,"journal":{"name":"Biomedical optics express","volume":"46 1","pages":""},"PeriodicalIF":2.9000,"publicationDate":"1999-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical optics express","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1117/12.349987","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 3
Abstract
For the past several years the US Air Force has led a research effort to investigate the thresholds and mechanisms for retinal damage from ultrashort laser pulses [i.e. nanosecond (10-9 sec) to femtosecond (10-15 sec) pulse widths]. The goal was to expand the biological database into the ultrashort pulse regime and thus to allow establishment of maximum permissible exposure limits for these lasers. We review the progress made in determining trends in retial damage by ultrashort laser pulses in the visible and near infrared, including variations in spot size and number of pulses. We also discuss the most likely damage mechanisms operative in this pulse width regime and discuss relevance to laser safety.
期刊介绍:
The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including:
Tissue optics and spectroscopy
Novel microscopies
Optical coherence tomography
Diffuse and fluorescence tomography
Photoacoustic and multimodal imaging
Molecular imaging and therapies
Nanophotonic biosensing
Optical biophysics/photobiology
Microfluidic optical devices
Vision research.