OPTIMASI FORMULA LULUR KRIM DAUN MAREME (Glochidion arborescens Blume.) SEBAGAI ANTIOKSIDAN DENGAN VARIASI TEPUNG JAGUNG DAN TEPUNG BERAS MENGGUNAKAN DESAIN FAKTORIAL

Indra Indra, Lia Rahmawati, Vera Nurviana
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Abstract

One way to maintain healthy skin is through skincare that incorporates natural ingredient scrubs. Free radicals contribute to the onset of cell damage associated with skin aging. Mareme leaves (Glochidion arborescens Blume.) contain antioxidants that can inhibit the reaction of free radicals in the body. The purpose of this study was to incorporate the ethanol extract of mareme leaves into a scrub formulation containing cornflour and rice flour. This study begins with a phytochemical screen, followed by TLC analysis of antioxidant activity using the DPPH-free radical scavenging test, evaluation of cream scrubs, and ANOVA data analysis. According to research, the ethanol extract of mareme leaves possesses a significant antioxidant activity of 4.32 parts per million. The effect of variations in cornstarch and rice flour on the formulation of cream scrubs was determined through organoleptic testing of all semisolid preparations, with an emphasis on different smells and colors; all formulas have a pH suitable for the skin of 4.5-8, and each formula contains less than 50 ppm of potent antioxidant activity. A significant value of 0.05 indicates that there is a significant difference between the four formulas based on the ANOVA test comparing IC50 values between preparations. It has to do with the addition of cornstarch scrub and rice flour to each formula. It can be concluded that the ethanol extract of mareme leaves (Glochidion arborescens Blume) possesses exceptional antioxidant activity. According to the stability test, the best formula for cream scrub preparations is formula 3.
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优化MAREME叶子霜配方(Glochidion arborescens Blume)。作为一种抗氧化剂,以玉米粉和米粉的变体使用阶梯式设计
保持皮肤健康的一种方法是使用含有天然成分磨砂膏的护肤产品。自由基会导致与皮肤老化相关的细胞损伤。云杉叶(Glochidion arborescens Blume.)含有抗氧化剂,可以抑制体内自由基的反应。本研究的目的是将马勒姆叶的乙醇提取物加入到含有玉米粉和米粉的磨砂配方中。本研究从植物化学筛选开始,随后使用dpph自由基清除试验进行TLC分析抗氧化活性,评估霜擦洗,并进行方差分析数据分析。据研究,马勒姆叶的乙醇提取物具有显著的抗氧化活性,为百万分之4.32。通过对所有半固体制剂的感官测试,重点研究了不同气味和颜色,确定了玉米淀粉和米粉含量的变化对乳膏磨砂配方的影响;所有配方都有适合皮肤的pH值为4.5-8,每个配方含有少于50ppm的有效抗氧化活性。通过比较制剂间IC50值的ANOVA检验,显著值为0.05表示四种制剂间存在显著性差异。这与在每种配方中加入玉米淀粉、磨砂膏和米粉有关。由此可见,海马莲叶乙醇提取物具有较强的抗氧化活性。根据稳定性测试,膏霜磨砂制剂的最佳配方为配方3。
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