A Rare Case of Burkholderia Cepacia Complex Septicemia in a Newborn

Q. M. Haque, Md Arifur Rahman, A. Ahmed, Shafi Ahmed
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Abstract

Burkholderia cepacia complex (Bcc) has rarely been reported to cause sepsis in newborns. A case in a newborn male was reported in a tertiary hospital in northern part of Bangladesh Khwaja Yunus Ali Medical College and Hospital, Sirajganj. The baby was born to a preeclamptic mother. He was quite well after a normal vaginal delivery. After 6 days, the baby was admitted to neonatal ward on complaint of dyspnea and fever. Antibiotic therapy was begun after samples for hemocultures were obtained with the suspicion of sepsis according to the clinical and laboratory findings. At the same time, he had a respiratory distress and grunting along with the absence of crying for a prolonged period of time. He was jaundiced. Blood culture revealed the presence of Bcc. The patient was sent to the Intensive Care Unit for resuscitation. Antibiotic susceptibility test of the blood specimen showed sensitivity to amikacin, ceftazidime, trimethoprim-sulfamethoxazole, meropenem and levofloxacin. Symptoms improved with medical support along with antimicrobial therapy. This case highlights the importance of diagnostic blood culture of an acute sepsis condition to obtain a specific etiological diagnosis and management.  KYAMC Journal Vol. 13, No. 03, October 2022: 181-182
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新生儿罕见的洋葱伯克氏菌复合败血症1例
洋葱伯克霍尔德菌复合体(Bcc)在新生儿中引起脓毒症的报道很少。孟加拉国北部西拉甘吉赫瓦贾·尤努斯·阿里医学院和医院的一家三级医院报告了一例新生儿男性病例。这个婴儿是一位先兆子痫的母亲所生。在正常的阴道分娩后,他很好。6天后,婴儿因呼吸困难和发热入住新生儿病房。根据临床和实验室结果,在怀疑败血症的情况下获得血液培养样本后开始抗生素治疗。与此同时,他有呼吸窘迫和咕噜声,并有很长一段时间没有哭泣。他患了黄疸病。血培养显示Bcc的存在。病人被送到加护病房接受复苏。血药敏试验对阿米卡星、头孢他啶、甲氧苄氨苄磺胺甲恶唑、美罗培南、左氧氟沙星敏感。在医疗支持和抗菌治疗下,症状得到改善。本病例强调了诊断性血培养对急性脓毒症的重要性,以获得特定的病因诊断和管理。KYAMC学报第13卷第03期,2022年10月:181-182
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