{"title":"Development of particle induced X-ray emission-computed tomography in Takasaki Advanced Radiation Research Institute, Japan Atomic Energy Agency","authors":"T. Satoh","doi":"10.1142/S0129083515500151","DOIUrl":null,"url":null,"abstract":"A new micro-particle induced X-ray emission-computed tomography (PIXE-CT) system was developed at Takasaki Ion Accelerators for Advanced Radiation Application in Japan Atomic Energy Agency. In this system, scanning transmission ion microscopy-CT was performed as well as PIXE-CT for three-dimensional (3D) measurement of major elements' distributions, which are required for corrections of X-ray yields due to energy losses of projectiles and absorption of X-rays. Moreover, maximum likelihood expectation maximization algorithm has been introduced to image reconstruction because higher spatial resolution can be obtained even with less X-ray yields. Consequently, 3D distribution of trace elements in a minute biological cell less than 100 μm has been successfully obtained.","PeriodicalId":14345,"journal":{"name":"International Journal of PIXE","volume":"50 1","pages":"147-152"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of PIXE","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1142/S0129083515500151","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
A new micro-particle induced X-ray emission-computed tomography (PIXE-CT) system was developed at Takasaki Ion Accelerators for Advanced Radiation Application in Japan Atomic Energy Agency. In this system, scanning transmission ion microscopy-CT was performed as well as PIXE-CT for three-dimensional (3D) measurement of major elements' distributions, which are required for corrections of X-ray yields due to energy losses of projectiles and absorption of X-rays. Moreover, maximum likelihood expectation maximization algorithm has been introduced to image reconstruction because higher spatial resolution can be obtained even with less X-ray yields. Consequently, 3D distribution of trace elements in a minute biological cell less than 100 μm has been successfully obtained.
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