Spectrum of incidental tumors in autopsy specimens: A histopathological analysis of 797 cases

B. Mohan, Lesitha Sivaraman, Surekha Vijayan, Aathira Das
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Abstract

INTRODUCTION: Autopsy supplemented with histopathological examination is important in finding the cause and manner of death. Although not common, neoplastic lesions are encountered in autopsy specimens. AIM: The aim of this study was to analyze the various incidental tumors (both benign and malignant) in medicolegal autopsies. MATERIALS AND METHODS: In this retrospective study, a total of 797 medicolegal autopsies done over a period of 2 years (January 2019–December 2020) were analyzed. Cases in which tumors were diagnosed were selected and details including age, gender, death scenario, and other relevant histopathological findings were noted in each of these. RESULTS: We noted 46 tumors out of 797 cases (5.8%). 18 (39.1%) were benign and 28 (60.9%) were malignant. Rare tumors such as central neurocytoma, diffuse astrocytoma, colonic schwannoma, and oligocystic serous cystadenoma of the pancreas were noted. CONCLUSIONS: We found 5.8% of neoplastic lesions in this study. Although the histopathological findings of neoplasms in the autopsies may not contribute to identifying the cause of death in most cases, there have been interesting cases that are a prime focus of academic and research data.
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尸检标本附带肿瘤谱:797例组织病理学分析
简介:尸检与组织病理学检查相结合,对于发现死因和死亡方式非常重要。虽然不常见,但在尸检标本中会遇到肿瘤病变。目的:本研究的目的是分析各种偶然肿瘤(良性和恶性)在法医尸检。材料与方法:在这项回顾性研究中,共分析了2年(2019年1月- 2020年12月)期间完成的797例法医尸检。选择被诊断为肿瘤的病例,并在每个病例中记录详细信息,包括年龄、性别、死亡情况和其他相关的组织病理学结果。结果:797例患者中发现肿瘤46例(5.8%)。良性18例(39.1%),恶性28例(60.9%)。罕见的肿瘤如中枢神经细胞瘤、弥漫性星形细胞瘤、结肠神经鞘瘤和胰腺少囊性浆液性囊腺瘤。结论:我们在本研究中发现了5.8%的肿瘤病变。虽然在大多数情况下,尸检中肿瘤的组织病理学发现可能无助于确定死亡原因,但有一些有趣的病例是学术和研究数据的主要焦点。
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审稿时长
32 weeks
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