UV Spectrophotometric Determination of Allopurinol and Benzbromarone in their Binary Mixture using Artificial Neural Networks and Genetic Algorithm- Artificial Neural Networks

Mohammad Nassar, Khalid A M Attia, A. A. Mohamad, Ragab A. M. Said, R. F. A. Gaber
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引用次数: 1

Abstract

Combination of ALP and BENZ has the advantages of greater therapeutic effect than with either drug alone. This combination causes manifold reduction in uric acid concentrations in plasma and urine as compared to double dose of the individual drug when used alone. Also, this combination helps to decrease the dose of each active ingredient, and as a result, decreases the side effects of each of component if given separately in high doses. (3)
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用人工神经网络和遗传算法紫外分光光度法测定别嘌呤醇和苯溴马隆的二元混合物
ALP与BENZ合用治疗效果优于单用。与单独使用双剂量药物相比,这种组合导致血浆和尿液中尿酸浓度的大幅度降低。此外,这种组合有助于减少每种活性成分的剂量,因此,如果以高剂量单独给药,可以减少每种成分的副作用。(3)
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