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Differential Pulse Voltammetric Determination of Paracetamol Using Activated Glassy Carbon Electrode 活性炭电极差分脉冲伏安法测定扑热息痛
Pub Date : 2021-05-21 DOI: 10.20431/2349-0403.0706004
Meselu Eskezia Ayalew, Dereje Yenealem Ayitegeb
The electrochemical property of paracetamol was investigated at a glassy carbon electrode and activated glassy carbon electrode. Differential pulse voltammetry and cyclic voltammetry were used as diagnostic techniques in the determination of paracetamol. The activated glassy carbon electrode exhibited excellent electro-catalytic behaviour for the oxidation of PAR as evidenced by the enhancement of the oxidation peak current and the shift in the oxidation peak potential to less positive values by (13mv) in comparison with a bare GCE. In the present work the activated glassy carbon electrode was prepared by activating 200 s in a time base technique at a potential of 1750 mV. The electrode process of paracetamol was studied and some the experimental parameters which affect the response paracetamol, such as pH, effect of PAR concentration and scan rate on AGC electrode. The analysis of cyclic voltammogram gave fundamental electrochemical parameters including the electroactive surface coverage, the electron transfer coefficient and the heterogeneous rate constant (ks). The variation of scan rate study shows that the system undergoes adsorption controlled process. The equation of the calibration curve was found to be: Ip=0.429C + 6.43, R2=0.993. The LOD and LOQ for the developed method were determined to be 8×10-8 mol L-1 and 2.6×10-7mol L-1 respectively. Phosphate buffer pH 7.0 was selected for analytical purpose.
研究了对乙酰氨基酚在玻碳电极和活化玻碳电极上的电化学性质。采用差分脉冲伏安法和循环伏安法测定对乙酰氨基酚的含量。活性炭电极对PAR的氧化表现出优异的电催化性能,与裸GCE相比,氧化峰电流增强,氧化峰电位向低正值偏移(13mv)证明了这一点。在1750 mV电势下,采用时间基法活化200 s制备了活性炭电极。研究了对乙酰氨基酚的电极过程,考察了影响对乙酰氨基酚反应的实验参数,如pH、PAR浓度和扫描速率对AGC电极的影响。循环伏安分析给出了基本的电化学参数,包括电活性表面覆盖率、电子传递系数和非均相速率常数。扫描速率的变化研究表明,该体系经历了吸附控制过程。标定曲线方程为:Ip=0.429C + 6.43, R2=0.993。该方法的定量限和定量限分别为8×10-8 mol L-1和2.6×10-7mol L-1。选择pH 7.0的磷酸盐缓冲液进行分析。
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引用次数: 2
Interphase Mass Transfer- An Important Mass Transfer Phenomenon 相间传质——一种重要的传质现象
Pub Date : 2021-01-01 DOI: 10.20431/2349-0403.0801003
Sunil jayant Kulkarni
Various theories were proposed in past to explain interphase mass transfer. For the case of gas liquid interphase mass transfer, it is well known fact that for every concentration in one phase, there is equilibrium concentration in other phase. The departure from this equilibrium state is causing the mass transfer. Wetted wall column experiments were considered for understanding of two resistance concepts [1,2]. Theories namely Film theory, penetration theory and surface renewal theory were proposed by various investigator to explain the interphase mass transfer and relation between diffusivity and mass transfer coefficient. Interphase mass transfer has been interesting area of investigation because of its complexity and importance in mass transfer in many processes[3,4].
过去提出了各种理论来解释相间传质。对于气液两相间传质,众所周知,对于一相中的每一个浓度,在另一相中都有一个平衡浓度。偏离平衡态引起了传质。为了理解两个阻力概念,我们考虑了湿壁柱实验[1,2]。各种研究者提出了膜理论、穿透理论和表面更新理论来解释相间传质以及扩散系数和传质系数之间的关系。由于质间传质在许多过程中的复杂性和重要性,质间传质一直是一个有趣的研究领域[3,4]。
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引用次数: 0
Toxicity Assessment of Heavy Metals in Soils around Transformers in University of Port Harcourt, Choba, Nigeria 尼日利亚乔巴港哈科特大学变压器周围土壤重金属毒性评价
Pub Date : 2021-01-01 DOI: 10.20431/2349-0403.0801004
Ayomide Adetutu Idowu, G. Iwuoha
Transformers has inbuilt dielectric substances and various forms of oils that serve various functions. In addition to transformer metal wares, these oils contain trace amount of various heavy metals which could leak and constitute environmental problems by adding up to the soil’s concentration. Soils have been found to be the major sink for heavy metals when released into the environment. It has been noted that most heavy metals do not undergo microbial or chemical degradation because they are nondegradable and as a result, there is bioaccumulation of their total concentrations after being released to the environment and it affects the food chain [1],[2],[3].
变压器有内置的介电物质和各种形式的油,服务于各种功能。除了变压器金属制品外,这些油还含有微量的各种重金属,这些重金属可能会泄漏,并通过增加土壤的浓度构成环境问题。土壤被发现是重金属释放到环境中的主要汇。人们注意到,大多数重金属由于其不可降解性而无法进行微生物或化学降解,因此释放到环境中后,其总浓度会发生生物积累,并影响食物链[1],[2],[3]。
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引用次数: 1
Bio Fuel Synthesis from Waste Feed Stocks-An Insight 从废弃原料中合成生物燃料的新见解
Pub Date : 2021-01-01 DOI: 10.20431/2349-0403.0801005
Parkar Saima Munawar, Mulukh Rutuja Santosh, Narhari Gautami Jagdish, Kulkarni Sunil Jayant
Solid waste generation through various human activities is increasing day by day. A large portion of solid waste contains agricultural and domestic waste. Agricultural waste is increasing rapidly with increase in population as there is hike in the food requirements. Globally, tons of food are wasted from the domestic kitchen and nearly equal amount of waste is also produced. Thus, it is necessary to treat these wastes properly and to use these wastes as a raw material to manufacture the other useful products to reduce the amount of waste generated. These two types of wastes can be utilized to manufacture useful products/energy generation at very low-cost rather than improper disposal [1].
人类各种活动产生的固体废物日益增多。大部分固体废物含有农业和家庭废物。随着人口的增加,粮食需求的增加,农业废弃物也在迅速增加。在全球范围内,家庭厨房浪费了数吨食物,同时也产生了几乎等量的废物。因此,有必要适当地处理这些废物,并将这些废物用作制造其他有用产品的原料,以减少废物的产生量。这两类废物可以被用来制造有用的产品/以非常低的成本发电,而不是不当处置[1]。
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引用次数: 0
Synthesis and Evaluation of Some Oxime Esters as New Attractants for Cockroaches 几种新型蟑螂引诱剂肟酯的合成及评价
Pub Date : 2020-01-01 DOI: 10.20431/2349-0403.0704002
A. Aliyu, J. Dauda, R. Larayetan
Cockroaches are disease causing agents. They are known to be carriers of protozoan, bacterial, helminth and viral diseases (Pandey et al, 1994). A study by Fakoorziba, et al (2010), isolated twenty five (25) different species of medically important bacteria with 22 of them Gram negative bacteria from P. americana and B. germanica. It has been found that P. americana may also play a role in the transmission of E. tenella among chicken and between chicken flocks (Jarujareet et al, 2019).
蟑螂是致病菌。已知它们是原生动物、细菌、蠕虫和病毒性疾病的携带者(Pandey等人,1994年)。Fakoorziba等人(2010)的一项研究分离了25种不同的医学上重要的细菌,其中22种是革兰氏阴性菌,来自美国P. americana和德国B. germanica。研究发现,美洲p.a americana也可能在鸡之间和鸡群之间传播tenella中发挥作用(Jarujareet et al, 2019)。
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引用次数: 0
Chemical and Physical Properties of Adulterated Honey and Developing Means of Identifying Adulterants 掺假蜂蜜的理化性质及鉴别掺假物的方法研究
Pub Date : 2020-01-01 DOI: 10.20431/2349-0403.0705003
M. Gemeda, Deresa Kebeba, Teferi Damto, G. Legesse
Honey is defined as a naturally sweet mixture produced by bees (Apis mellifera) from the nectar or from secretions of living parts of plants or excretions of plant sucking insects on the living parts of plants transform and combine with specific substances of their own (such as enzymes), deposit, dehydrate, store and leave in the beeswax honeycombs to ripen and mature. It is typical sugary foodstuff; according to present-day regulations, apart from other forms of honey no other or additives can be added to it. The aim of this study was to develop identification means of adulterated honey using chemical and physical analysis. Adulteration of honey was obtained by mixing and homogenizing major honey adulterants so far known like sugar, banana, “sheb”, molasses and water with different ratio. Moisture content, electrical conductivity, PH, ash, free acidity (FA) and Hydroxymehylfurfural of adulterated and pure honey were determined. The pure honey free acidity content is significantly different from adulterated honey in all treatments group (P<0.05). Highest FA content (458.33±1.66 meq/kg) recorded in (honey: sugar: water: sheb) treatment. Adulteration affects the purity and quality properties of honey, by using the ash content, free acidity and electrical conductivity adulteration can be identified and color parameter is not recommended for identification of adulterated honey.
蜂蜜被定义为蜜蜂(Apis mellifera)从花蜜或植物活部分的分泌物或植物吸吮昆虫在植物活部分的排泄物中产生的天然甜味混合物,它们与自己的特定物质(如酶)转化并结合,沉积,脱水,储存并留在蜂蜡蜂巢中成熟和成熟。它是典型的含糖食品;根据目前的规定,除其他形式的蜂蜜外,不能添加其他或添加剂。本研究的目的是建立用化学和物理分析方法鉴别掺假蜂蜜的方法。将目前已知的主要蜂蜜掺假物如糖、香蕉、“sheb”、糖蜜和水按不同比例混合均匀后得到蜂蜜掺假。测定了掺假蜂蜜和纯蜂蜜的含水量、电导率、PH、灰分、游离酸度(FA)和羟甲基糠醛。各处理组纯蜂蜜游离酸含量与掺假蜂蜜差异显著(P<0.05)。在(蜂蜜:糖:水:羊奶)处理中,FA含量最高(458.33±1.66 meq/kg)。掺假影响蜂蜜的纯度和品质特性,通过灰分含量、游离酸度和电导率可以鉴别掺假,颜色参数不推荐用于鉴别掺假蜂蜜。
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引用次数: 2
Fingerprint Intermolecular Interactions of Sodium and Potassium Complexes 钠和钾配合物分子间相互作用的指纹图谱
Pub Date : 2020-01-01 DOI: 10.20431/2349-0403.0709003
M. Bhavya, R. Malarvizhi
The complex of sodium and potassium salts is characterized by using UV-Visible, FT-IR, NMR, Singlecrystal X-ray diffraction, Hirshfeld surfaces, and Fingerprint plots. The crystal belongs to the monoclinic system and p121/n1, p21/n space group. The corresponding peaks for chlorine atoms are absent in the NMR spectra of the complexes. The small red spot in Hirshfeld surfaces indicates the presence of CH...π interactions in the sodium complex. Absence of Metal...Metal interactions were also observed in both sodium and potassium complex. Fingerprint plots of Hirshfeld surfaces were used to detect and examine the percentage of hydrogenbonding interactions.
通过紫外可见光谱、红外光谱、核磁共振光谱、单晶x射线衍射、赫希菲尔德表面和指纹图谱对钠钾盐配合物进行了表征。晶体属于单斜晶系和p121/n1、p21/n空间群。在配合物的核磁共振光谱中没有氯原子的相应峰。赫希菲尔德表面的小红点表明CH的存在。钠络合物中的π相互作用。缺金属……在钠和钾络合物中也观察到金属相互作用。赫希菲尔德表面的指纹图谱用于检测和检验氢键相互作用的百分比。
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引用次数: 0
HPLC Method for Simultaneous Determination of Ascorbic acid, Phenylephrine, Paracetamol, Caffeine in Their Pure and Dosage Forms 高效液相色谱法同时测定抗坏血酸、苯肾上腺素、对乙酰氨基酚、咖啡因的纯和剂型
Pub Date : 2020-01-01 DOI: 10.20431/2349-0403.0706002
Yara M. Elkady, Sobhy M. El-Adl, M. Baraka, M. Sebaiy
An isocratic HPLC method has been developed for determination of ascorbic acid, phenylephrine, paracetamol, and caffeine in their pure and tablet forms. Separation was carried out at room temperature on an Kinetex 2.6 C18 100A (4.6 mm × 100 mm) column using a mobile phase of 0.05 M potassium dihydrogen phosphate buffer (pH 3.50 by ortho-phosphoric acid): acetonitrile: methanol (70:20:10). The flow rate was 1 mL/min, maximum absorption was measured at 220 nm and linearity was in the range of 1-50 μg/mL for all drugs. The retention times of ascorbic acid, phenylephrine, paracetamol and caffeine were reported to be 1.83, 2.94, 3.74 and 5.13 minutes, respectively, indicating a very short analysis time compared with other reported methods. Also, limits of detection were reported to be 0.76, 0.82, 0.47 and 0.24 μg/mL for ascorbic acid, phenylephrine, paracetamol, and caffeine respectively, showing a high degree of the method sensitivity. The proposed method was validated in terms of linearity, accuracy, precision and robustness according to ICH guidelines and results were compared statistically with reference methods in respect of precision and accuracy.
建立了一种测定抗坏血酸、苯肾上腺素、扑热息痛和咖啡因纯品和片剂含量的HPLC法。采用Kinetex 2.6 C18 100A (4.6 mm × 100 mm)色谱柱,室温分离,流动相为0.05 M磷酸二氢钾缓冲液(正磷酸pH为3.50):乙腈:甲醇(70:20:10)。流速为1 mL/min,在220 nm处测得最大吸光度,在1 ~ 50 μg/mL范围内呈线性关系。据报道,抗坏血酸、苯肾上腺素、对乙酰氨基酚和咖啡因的保留时间分别为1.83、2.94、3.74和5.13分钟,与其他报道的方法相比,分析时间非常短。对抗坏血酸、苯肾上腺素、对乙酰氨基酚和咖啡因的检出限分别为0.76、0.82、0.47和0.24 μg/mL,具有较高的灵敏度。根据ICH指南对该方法进行线性、准确度、精密度和稳健性验证,并与参考方法的精密度和准确度进行统计比较。
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引用次数: 0
Assessment of Water Needs in Ezinihitte Local Government Area of Imo State, Nigeria 尼日利亚伊莫州Ezinihitte地方政府地区用水需求评估
Pub Date : 2020-01-01 DOI: 10.20431/2349-0403.0708002
T. Nnadozie, V. A. Wirnkor
The study is aimed at assessing the water needs of the people of Ezinihitte LGA. This was cropped from the problem that emanated from the observed Government efforts on water provision, which had remained grossly inadequate to cover the entire communities, the dearth of available water facilities and how the villagers trek to long distances in search of water. Major issues of discourse included the distribution of water to households and how their water needs are tackled. Three hypotheses were tested and the questionnaire survey method was employed. The multi-stage sampling technique was used, and the sample size was 416. Data from the questionnaire were collected, tabulated into frequency distribution table and analyzed by using regression, correlation and ANOVA techniques. While testing the hypothesis, it was found that the quantity of water supplied was insufficient in the study area. Data from different sources show high positive correlation coefficient of variables indicating significant relationships between the quantities of water currently consumed and that required to be consumed. The study was concluded by recommending the involvement of the federal, state and local governments and other interest groups as well as the benefitting communities in water projects.
该研究旨在评估Ezinihitte LGA人民的水需求。这是由于所观察到的政府在供水方面的努力所产生的问题,这些努力仍然远远不足以覆盖整个社区,缺乏可用的供水设施以及村民如何长途跋涉寻找水。讨论的主要问题包括向家庭分配水以及如何解决他们的水需求。检验三个假设,采用问卷调查法。采用多阶段抽样技术,样本量为416份。收集问卷数据,制成频率分布表,运用回归、相关和方差分析技术进行分析。在验证假设的过程中,发现研究区域的供水量不足。来自不同来源的数据显示,变量之间的正相关系数很高,表明目前消耗的水量与需要消耗的水量之间存在显著关系。这项研究的结论是建议联邦、州和地方政府以及其他利益团体以及受益社区参与水利项目。
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引用次数: 0
Biosensors for Bacteria for Artwork 用于艺术品的细菌生物传感器
Pub Date : 2020-01-01 DOI: 10.20431/2349-0403.0703001
Georgia-Paraskevi Nikoleli
An artwork such as a painting can be a good example of a place that microorganisms such as bacteria and fungi can colonize. Bacteria have a part in deteriorating, and preserving artwork and paintings. Bacterial processes may produce colored pigments work arts. Bacterial culturing was widely used to explore their pigments by scientists and artists. The same pigments are also utilized in the processes of coloring various foods, textiles, and paints. Microbes may also play a significant role to deterioration and preservation of art work. The metabolic steps of microbes can affect the ancient cave art and may cause deteriorative harm to these works of arts. Bacteria may cause both deteriorative and resolving. A number of bacteria have been utilized in restoring artworks and and also in their preservation and stopping their deterioration.
像绘画这样的艺术品可以是细菌和真菌等微生物可以定居的一个很好的例子。细菌在艺术品和绘画的变质和保存中起着一定的作用。细菌过程可以产生彩色颜料。细菌培养被科学家和艺术家广泛用于探索它们的色素。同样的色素也用于各种食品、纺织品和油漆的着色过程中。微生物对艺术品的变质和保存也起着重要的作用。微生物的代谢步骤会影响古代洞穴艺术,并可能对这些艺术作品造成变质伤害。细菌可能导致变质和溶解。许多细菌已被用于修复艺术品,也用于保存和防止它们变质。
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引用次数: 0
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International Journal of Advanced Research in Chemical Science
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