Moebius syndrome: A review of literature

Abstract

Moebius syndrome is a congenital neurological disorder, which frequently shows facial diplegia with bilateral lateral rectus palsy, but there are variations. The definition and diagnostic criteria for Moebius syndrome vary among authors, it is defined as congenital facial weakness with abnormal ocular abduction. Deformities such as muscular dystrophies and mental retardation have also been associated with this syndrome. The list of signs and symptoms mentioned in various sources for Moebius syndrome includes more than 20 peculiar features. This review of literature includes classification and grading system of Moebius syndrome, their features, etiology, and management.