Computation Prediction of the Therapeutic Effect of Metal Stent Implantation for Coronary Bifurcation

Abstract

A good understanding of the characteristics behavior of blood flow is significant for exploring the formation mechanism and process of atherosclerosis (AS), grasping the pathogenesis of AS, and providing effective theoretical guidance for clinical treatment of AS. To predict the influence of plaque on hemodynamics and the therapeutic effect of stent interventional treatment on stenosis artery, the coronary bifurcation models with/without stenosis and with stent implantation were constructed to analyze the hemodynamic characteristics in three cases using fluid-solid interaction method based on COMSOL software. The dynamic velocity, streamline, pressure, Von Mises stress, and displacement distributions in the coronary artery were obtained in these studies. Results show that the velocity of the plaque increased sharply, and the peripheral tissues of the plaque are more prone to the risk of injury because of the higher stress. The blood flow velocity tends to be stable in the stented artery and the velocity distribution is uniform, indicating that the blood supply of branch vessels is further improved, which is conducive to the normal blood supply and stable blood flow.