{"title":"Inhibition of human leukocyte elastase by natural fragrant extracts of aromatic plants","authors":"S. Baylac, P. Racine","doi":"10.1016/j.ijat.2004.09.008","DOIUrl":null,"url":null,"abstract":"<div><p><span><span><span><span>The influence of 37 essential oils, absolutes, resinoids, oleoresins and natural plant extracts were tested on the </span>enzymatic activity of human leukocyte </span>elastase HLE (EC 3.4.21.37). Among them, poplar bud absolute, </span>rosemary extract, </span>benzoin<span> resinoid and turmeric oleoresin had an inhibitory activity significantly higher than the reference, ursolic acid<span>. Specifically, turmeric oleoresin was the most potent inhibitor of HLE. Essential oils tested were in their majority totally inactive. Because of the specific role of human leukocyte elastase in the inflammatory process, its inhibition by such absolutes, resinoids, oleoresins or plant extracts should encourage their use in Aromatherapy and in cosmetic products for irritated, reactive and/or senescent epidermis.</span></span></p></div>","PeriodicalId":100691,"journal":{"name":"International Journal of Aromatherapy","volume":"14 4","pages":"Pages 179-182"},"PeriodicalIF":0.0000,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijat.2004.09.008","citationCount":"28","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Aromatherapy","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0962456204000943","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 28
Abstract
The influence of 37 essential oils, absolutes, resinoids, oleoresins and natural plant extracts were tested on the enzymatic activity of human leukocyte elastase HLE (EC 3.4.21.37). Among them, poplar bud absolute, rosemary extract, benzoin resinoid and turmeric oleoresin had an inhibitory activity significantly higher than the reference, ursolic acid. Specifically, turmeric oleoresin was the most potent inhibitor of HLE. Essential oils tested were in their majority totally inactive. Because of the specific role of human leukocyte elastase in the inflammatory process, its inhibition by such absolutes, resinoids, oleoresins or plant extracts should encourage their use in Aromatherapy and in cosmetic products for irritated, reactive and/or senescent epidermis.
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