Prevalence and risk factors associated with primary open angle glaucoma in diabetic patients in a tertiary care centre

N. Rajendran, I. Isaac, Janie Salor, J. Jacob
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Abstract

Primary open angle glaucoma is the most common form of glaucoma accounting for at least half of all the glaucomas. It is also known as chronic open angle glaucoma and chronic simple glaucoma. It is usually asymptomatic until significant visual field loss has happened. Patients usually present with considerable amount of visual field loss in one eye and advanced disease in the other eye. Diabetes Mellitus is one among the risk factors for POAG. Objectives ▪ To study the hospital-based prevalence of POAG among the diabetic patients attending Sree Mookambika Institute of Medical Sciences (SMIMS), Kulasekharam. ▪ To study the risk factors associated with POAG. ▪ To screen all diabetic patients for glaucoma. Methods: In this study, 181 diabetic patients, both insulin dependent and non-insulin dependent, attending Sree Mookambika Institute of Medical Sciences, who came directly to Department of Ophthalmology or who were referred here for evaluation, between December 2016 and August 2018 had been screened to rule out Primary Open Angle Glaucoma (POAG). Results: The results of the study show a clear-cut evidence of increased incidence of POAG in diabetic patients, which was 5%. There is a significant association between age and POAG. No significant association was found between gender and POAG. No significant association was found between duration of DM and prevalence of POAG. Conclusion: Primary Open Angle glaucoma is mostly asymptomatic until significant visual field loss has occurred. Patients usually presents with significant visual field loss in one eye and advanced disease in the other eye. It is associated with irreversible blindness. Thus, the public health importance of detecting undiagnosed and treatable glaucoma, as blindness has economic and societal consequences for the rest of an individual’s life. Several studies have shown an association between POAG and diabetes. From my study, I came to a conclusion that there is a clear-cut evidence of increased incidence of POAG in diabetic patients, which was 5%. Study also showed significant association between age and POAG. However, no significant association was found between gender and POAG as well as between duration of DM and prevalence of POAG.
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三级保健中心糖尿病患者原发性开角型青光眼的患病率及相关危险因素
原发性开角型青光眼是最常见的青光眼,占所有青光眼的一半以上。又称慢性开角型青光眼和慢性单纯性青光眼。它通常是无症状的,直到发生明显的视野丧失。患者通常表现为一只眼睛大面积视野丧失,另一只眼睛病情进展。糖尿病是POAG的危险因素之一。目的▪研究库拉塞克哈拉姆Sree Mookambika医学科学研究所(SMIMS)的糖尿病患者在医院的POAG患病率。▪研究与POAG相关的危险因素。▪对所有糖尿病患者进行青光眼筛查。方法:本研究选取2016年12月至2018年8月在Sree Mookambika医学科学研究所直接就诊或转诊的181例胰岛素依赖型和非胰岛素依赖型糖尿病患者进行筛查,排除原发性开角型青光眼(POAG)。结果:研究结果明确表明糖尿病患者POAG发生率增加,为5%。年龄与POAG有显著的相关性。性别与POAG之间无显著关联。糖尿病持续时间与POAG患病率之间未发现显著相关性。结论:原发性开角型青光眼在发生明显的视野丧失前大多无症状。患者通常表现为一只眼睛明显的视野丧失,另一只眼睛病情进展。它与不可逆失明有关。因此,发现未确诊和可治疗的青光眼具有公共卫生重要性,因为失明会对个人的余生产生经济和社会后果。一些研究表明POAG与糖尿病之间存在关联。从我的研究中,我得出了一个结论,有明确的证据表明糖尿病患者POAG的发病率增加了,这是5%。研究还表明,年龄与POAG之间存在显著相关性。然而,性别与POAG之间以及糖尿病持续时间与POAG患病率之间没有显著关联。
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