A nine-month-old girl with respiratory failure and rhomboencephalitis.

IF 7.4 1区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Corrosion Science Pub Date : 2015-09-01 DOI:10.1155/2015/656932
Cheryl Pz Foo, Andrew McDermid, Elsie Grudeski, Tim F Booth, Jared Bullard
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一名九个月大的女孩,患有呼吸衰竭和斜方形脑炎。
病例介绍:2014年9月,马尼托巴省北部一名9个月大的女婴出现,她的脚底有3天的水疱疹史。她被诊断为手足口病,并从当地护理站出院。在接下来的24小时内,她出现咳嗽和发烧,导致进行性呕吐、腹泻和呼吸困难,导致大量氧气需求,这导致她被转移到三级保健中心。入院时,她因呼吸衰竭和低血压需要插管和液体复苏。经体格检查,她不发烧。呼吸检查双侧弥漫性脆裂,呼吸音粗大。心脏和腹部检查正常。唯一剩下的皮疹包括右脚足底红斑基础上的水疱性病变。实验室检查显示白细胞计数4.3×109/L,其中绝对中性粒细胞计数1.7×109/L。其余全血细胞计数、肝酶水平、肾功能和电解质均正常。在使用万古霉素和头孢曲松之前进行的血液和气管内插管培养均为阴性。尿液分析未发现白细胞或亚硝酸盐;尿培养为全敏感大肠杆菌阳性(2×106 CFU/L)。入院后1天取脑脊液,血流动力学好转,镜检白细胞计数28×106细胞/L,其中淋巴细胞66%,中性粒细胞8%,单核细胞26%,葡萄糖5 mmol/L,蛋白0.21 g/L,少量红细胞。肠道病毒和单纯疱疹病毒的细菌培养和聚合酶链反应(PCR)均为阴性。粪便电子显微镜检查为阴性,但粪便病毒培养尚未完成。胸部x线显示右肺中叶浸润。鼻咽吸液和支气管肺泡灌洗液检测呼吸道病毒,包括腺病毒、人冠状病毒OC43、229E和NL63、呼吸道合胞病毒A和B、流感A和B、副流感1、2、3和4、肠道病毒、鼻病毒A、B和C、bocavavirus 1和2以及人偏肺病毒均为阴性。抗酸杆菌涂片及培养、支气管肺泡灌洗细菌培养、真菌培养均为阴性。入院第2天,患者上肢无法活动。同日对头部和脊柱进行磁共振成像,发现脑干背侧弥散受限,脑颈交界处、颈椎、胸腰椎等部位信号强度延长,提示横脊髓炎伴菱形脑炎。由于没有检测到感染因子,怀疑是自身免疫介导的过程。三天的脉冲甲基强的松龙疗程没有改善。患者对呼吸机的需求增加,包括入院第6至11天的高频喷射通气。在接下来的五天里,病人在支持性护理下慢慢康复。患者于入院第14天拔管,第37天出院,右臂活动能力残余受损。出院两个月后,患者就诊时右臂举到面部有改善,但仍存在困难,且无法将右臂举到肩膀以上。她之后是物理治疗,职业治疗和儿科神经病学。
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来源期刊
Corrosion Science
Corrosion Science 工程技术-材料科学:综合
CiteScore
13.60
自引率
18.10%
发文量
763
审稿时长
46 days
期刊介绍: Corrosion occurrence and its practical control encompass a vast array of scientific knowledge. Corrosion Science endeavors to serve as the conduit for the exchange of ideas, developments, and research across all facets of this field, encompassing both metallic and non-metallic corrosion. The scope of this international journal is broad and inclusive. Published papers span from highly theoretical inquiries to essentially practical applications, covering diverse areas such as high-temperature oxidation, passivity, anodic oxidation, biochemical corrosion, stress corrosion cracking, and corrosion control mechanisms and methodologies. This journal publishes original papers and critical reviews across the spectrum of pure and applied corrosion, material degradation, and surface science and engineering. It serves as a crucial link connecting metallurgists, materials scientists, and researchers investigating corrosion and degradation phenomena. Join us in advancing knowledge and understanding in the vital field of corrosion science.
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