"Point of no return" in diabetic neuropathies: delusion or crime? International consensus

Abstract

Polyneuropathy in patients with diabetes mellitus is manifested by a lesion of peripheral sensory, motor and autonomic nervous system. Different severity of damage of sensory, motor and autonomic fibers in typical and atypical forms of diabetic polyneuropathy, require a differentiated approach to therapy, but not the rejection of its implementation. In an interdisciplinary consensus, consultations are held with physicians from different regions of the Russian Federation, and modern methods of diagnosing and assessing the severity of diabetic polyneuropathies, which determine the algorithm for treating patients, are discussed. Keywords: diabetic polyneuropathy, neuropathic pain, gabapentinoids, antidepressants, thioctic acid, benfotiamine, neurotropic therapy, pentasinergy, neuroplasticity, point of no return, therapeutic nihilism, interdisciplinary consensus on DPN.