Review on Rational Use of Antmicrobials in Veterinary Practice

Selamawit Fentahun Ali
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引用次数: 2

Abstract

Veterinary drugs are used as therapeutic, prophylactic and growth promotion. The review was conducted with the aim of assessing the rational use of veterinary antimicrobials. Veterinary drugs are used in livestock sector either rationally or irrationally. Rational use of veterinary drugs means sick animals receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period, and at the lowest cost. Whereas irrational drug use are characterized by over prescription, omission, the use of inappropriate dosage, incorrect duration, misuse of drug, take unnecessary risk, over use /frequent use of drugs and not stick with withdrawal period of a drug. The review indicates veterinary drugs used irrationally due to lack of knowledgeable of healthcare providers, lack of treatment guidelines, essential drug lists and national formularies, lack of diagnostic support services such as laboratory services, self-medication and purchasing of antibiotics directly from pharmacies, street vendors or markets and inadequate supply of veterinary drugs. Irrational use of drugs leads to antimicrobial resistance which is the current global health threat to animals and human being. Hence, veterinary drugs, especially, antimicrobial agents should be prudently used, improve availability of key essential drugs on stock through good drug supply management to reduce misuse of drugs and therapeutic failure, keep the withdrawal period to safeguard the public as well the livestock from drug residual effects and development of antimicrobial resistance are recommended.
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抗菌药物在兽医实践中的合理应用综述
兽药用于治疗、预防和促进生长。进行审查的目的是评估兽医抗菌药物的合理使用。兽药在畜牧业中的使用存在着合理和不合理的问题。合理使用兽药是指患病动物接受适合其临床需要的药物,剂量符合其个人需要,时间充足,费用最低。不合理用药主要表现为处方过多、遗漏、用量不当、用药时间不正确、滥用药物、冒不必要的风险、用药过量/频繁、不遵守停药期限等。审查表明,兽药使用不合理,原因是缺乏卫生保健提供者的知识,缺乏治疗指南、基本药物清单和国家处方,缺乏诊断支助服务,如实验室服务、自我药疗和直接从药店、街头摊贩或市场购买抗生素,以及兽药供应不足。药物的不合理使用导致抗菌素耐药性,这是当前全球动物和人类健康的威胁。因此,应谨慎使用兽药,特别是抗菌药物,通过良好的药物供应管理,提高关键基本药物的库存可获得性,减少药物滥用和治疗失败,控制停药期,以保护公众和牲畜免受药物残留效应和耐药性的影响。
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