COVID-19 Pneumonia in a Patient in Her Seventies that Improved without Antiviral Drug Treatment: A Case Study

Y. Miyazawa, K. Yanagisawa, Y. Ogawa, H. Koiso, Y. Tokue, H. Handa
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Abstract

As no specific therapeutic agents have been established yet for coronavirus disease 2019 (COVID-19), the illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), symptomatic therapy is the mainstay of treatment Although the “Concept of antiviral treatment for COVID-19, First edition” published by the Japanese Association for Infectious Diseases recommends the use of antiviral medication for infected individuals over the age of 50 years, we have documented the case of a 73-year-old woman with COVID-19 pneumonia who improved without antiviral medication The patient became infected with SARS-CoV-2 on the cruise ship, Diamond Princess, and first tested positive for SARS-CoV-2, by the RT-PCR test, on February 15, 2020 She was admitted to another hospital with fever and pneumonia on February 16, and on February, the pneumonia worsened in severity, she was transferred to our hospital However, her condition improved spontaneously within a few days, without any antiviral medication This report is very valuable for documenting the natural history of COVID-19 pneumonia and can be considered as a reference case for formulating strategies for antiviral drug administration for COVID-19 patients in the future
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一位70多岁患者的COVID-19肺炎在没有抗病毒药物治疗的情况下得到改善:一个案例研究
虽然日本传染病学会出版的《2019冠状病毒病抗病毒治疗概念第一版》建议50岁以上的感染者使用抗病毒药物,但由于目前还没有针对这种由严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)引起的疾病2019冠状病毒病(COVID-19)的特异性治疗剂,对症治疗仍是主要的治疗方法。我们记录了一名73岁的女性COVID-19肺炎病例,她在未经抗病毒药物治疗的情况下病情有所好转,她在钻石公主号游轮上感染了SARS-CoV-2,并于2020年2月15日首次通过RT-PCR检测检测出SARS-CoV-2阳性,她于2月16日因发烧和肺炎入住另一家医院,2月肺炎严重恶化,她被转移到我医院。该报告对记录COVID-19肺炎的自然史具有重要价值,可作为今后制定COVID-19患者抗病毒药物给药策略的参考案例
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