Pub Date : 2020-11-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.839
Tomohide Okinaka, Hiroki Yamakuchi, Masanari Komatsu, H. Saeki
{"title":"A Case of Lung Abscess Caused by Hyperviscous Klebsiella pneumoniae subsp. ozaenae","authors":"Tomohide Okinaka, Hiroki Yamakuchi, Masanari Komatsu, H. Saeki","doi":"10.11150/KANSENSHOGAKUZASSHI.94.839","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.839","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81520040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.855
T. Adachi, M. Sano, Nanae Aritaka
{"title":"Exposure Leading to COVID-19 Reported by Patients in Tokyo","authors":"T. Adachi, M. Sano, Nanae Aritaka","doi":"10.11150/KANSENSHOGAKUZASSHI.94.855","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.855","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89707798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.808
R. Tsukada, K. Mori, S. Usuku, Makoto Kumazaki, Tetsuya Yoshida
{"title":"An Outbreak of Gastroenteritis Caused by Human Astrovirus Serotype 8 in Nagano Prefecture, Japan.","authors":"R. Tsukada, K. Mori, S. Usuku, Makoto Kumazaki, Tetsuya Yoshida","doi":"10.11150/KANSENSHOGAKUZASSHI.94.808","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.808","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77217910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.579
Kwang-Hoon Lee
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the novel virus, SARS-CoV-2 The clinical spectrum of COVID-19 varies from asymptomatic infection to severe pneumonia The COVID-19 epidemic started at the end of 2019 in Wuhan, China, and the disease has now spread to the entire world The rapid spread of the infection worldwide led the WHO to declare the outbreak a pandemic on March 11, 2020 Herein, we report three patients with COVID-19 admitted to Atsugi City Hospital, who contracted the infection on the cruise ship, Diamond Princess, which was one of the early sites of outbreak of COVID-19 The three patients had different backgrounds, including age, sex and underlying disease profile, and each had a different clinical course However, all three tested persistently positive by the PCR test for more than 4 weeks, which is longer than the average reported period of positivity In this report, we discuss the interpretation of persistently positive results of PCR for SARS-CoV-19, the appropriate instructions for these patients, and the optimal timing of discharge home of these patients, considering the available medical resources
{"title":"Three Cases of COVID-19 with Persistently Positive Results of the PCR Test for Over 4 Weeks","authors":"Kwang-Hoon Lee","doi":"10.11150/KANSENSHOGAKUZASSHI.94.579","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.579","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the novel virus, SARS-CoV-2 The clinical spectrum of COVID-19 varies from asymptomatic infection to severe pneumonia The COVID-19 epidemic started at the end of 2019 in Wuhan, China, and the disease has now spread to the entire world The rapid spread of the infection worldwide led the WHO to declare the outbreak a pandemic on March 11, 2020 Herein, we report three patients with COVID-19 admitted to Atsugi City Hospital, who contracted the infection on the cruise ship, Diamond Princess, which was one of the early sites of outbreak of COVID-19 The three patients had different backgrounds, including age, sex and underlying disease profile, and each had a different clinical course However, all three tested persistently positive by the PCR test for more than 4 weeks, which is longer than the average reported period of positivity In this report, we discuss the interpretation of persistently positive results of PCR for SARS-CoV-19, the appropriate instructions for these patients, and the optimal timing of discharge home of these patients, considering the available medical resources","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85108626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.542
Y. Ogawa, S. Yoshihara, Toshihiko Nagata, Taisuke Akiyama, J. Kumasawa, M. Kono, H. Kohata, K. Nishida, I. Gohma
The patient, an 83-year-old woman, lived with her daughter, at whose workplace, a person had been diagnosed as having COVID-19 The daughter was admitted to the hospital for pneumonia, however, the results of the PCR test for SARS-CoV-2 performed twice were negative The patient developed fever a few days later, and visited an outpatient clinic for patients with fever and a history of travel abroad The result of a nasal swab PCR test was negative, and antibiotics were prescribed While the fever gradually subsided, the patient began to experience dyspnea Therefore, she visited the outpatient clinic again for a repeat nasal swab test Meanwhile, the dyspnea became severe and she was transported to our hospital Immediately after admission, she was intubated and initiated on mechanical ventilation A nasal swab and a specimen of lower respiratory tract secretions were submitted for COVID-19 testing by PCR, and while the nasal swab test result was negative again, the lower respiratory tract specimen yielded a positive result�E�EThe possibility of false-negative results of PCR testing for SARS-CoV-2 should be borne in mind in close contacts or strongly suspected cases of COVID-19 PCR testing of specimens of lower respiratory tract secretions might be necessary for suspected cases of COVID-19 pneumonia
{"title":"A Case of COVID-19 Pneumonia in an 83-year-old Woman Living with a Suspected SARS-CoV-2 Carrier, Who Repeatedly Tested Negative by the PCR Test","authors":"Y. Ogawa, S. Yoshihara, Toshihiko Nagata, Taisuke Akiyama, J. Kumasawa, M. Kono, H. Kohata, K. Nishida, I. Gohma","doi":"10.11150/KANSENSHOGAKUZASSHI.94.542","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.542","url":null,"abstract":"The patient, an 83-year-old woman, lived with her daughter, at whose workplace, a person had been diagnosed as having COVID-19 The daughter was admitted to the hospital for pneumonia, however, the results of the PCR test for SARS-CoV-2 performed twice were negative The patient developed fever a few days later, and visited an outpatient clinic for patients with fever and a history of travel abroad The result of a nasal swab PCR test was negative, and antibiotics were prescribed While the fever gradually subsided, the patient began to experience dyspnea Therefore, she visited the outpatient clinic again for a repeat nasal swab test Meanwhile, the dyspnea became severe and she was transported to our hospital Immediately after admission, she was intubated and initiated on mechanical ventilation A nasal swab and a specimen of lower respiratory tract secretions were submitted for COVID-19 testing by PCR, and while the nasal swab test result was negative again, the lower respiratory tract specimen yielded a positive result�E�EThe possibility of false-negative results of PCR testing for SARS-CoV-2 should be borne in mind in close contacts or strongly suspected cases of COVID-19 PCR testing of specimens of lower respiratory tract secretions might be necessary for suspected cases of COVID-19 pneumonia","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77148087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.500
Hiroki Soma, Tomohiro Hosoda, Mamoru Ito, Shinya Nagae, Kazunori Furuhashi, M. Sakamoto, Hiroyuki Nozaki, H. Shimizu, N. Okabe
The number of the patients with coronavirus disease 2019 (COVID-19) is increasing, and shortage of hospital beds for these patients is a cause for serious concern Here, we report the clinical course of 11 patients who were admitted to our hospital with COVID-19 that developed during their quarantine period in a large cruise ship, and discuss the factors associated with the disease severity and length of hospitalization The median age of the 11 patients was 62 years, and 36% were men The disease severity was mild in 7 patients, moderate in 4 patients, and severe in none of the patients The median time from symptom onset to disease remission was 13 days for patients with moderately severe disease, and 7 days for patients with mild disease The median interval from symptom onset to confirmation of the first negative result of PCR was 16 days for patients with moderately severe disease, and 14 days for patients with mild disease The median time from symptom onset to discharge was 22 5 days for patients with moderately severe disease cases, and 16 days for patients with mild disease Some patients needed prolonged hospitalization because of persistently positive results of PCR even after remission of symptoms Comparison between the patient groups with moderately severe disease and mild disease showed that the patients with moderately severe disease were older and had higher serum ferritin and serum amyloid protein (SAA) levels than the patients with mild disease Even in patients with mild to moderate COVID-19, two to three weeks were required from symptom onset to confirmation of the first negative result of PCR, and this was one of the major factors for prolonged hospitalization The serum ferritin levels and SAA levels might be predictors of the disease severity
{"title":"Clinical Course of 11 Cases of SARS-CoV-2 Infection Occurred in A Large Cruise Ship： Factors Associated with Severity and Prolonged Hospitalization","authors":"Hiroki Soma, Tomohiro Hosoda, Mamoru Ito, Shinya Nagae, Kazunori Furuhashi, M. Sakamoto, Hiroyuki Nozaki, H. Shimizu, N. Okabe","doi":"10.11150/KANSENSHOGAKUZASSHI.94.500","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.500","url":null,"abstract":"The number of the patients with coronavirus disease 2019 (COVID-19) is increasing, and shortage of hospital beds for these patients is a cause for serious concern Here, we report the clinical course of 11 patients who were admitted to our hospital with COVID-19 that developed during their quarantine period in a large cruise ship, and discuss the factors associated with the disease severity and length of hospitalization The median age of the 11 patients was 62 years, and 36% were men The disease severity was mild in 7 patients, moderate in 4 patients, and severe in none of the patients The median time from symptom onset to disease remission was 13 days for patients with moderately severe disease, and 7 days for patients with mild disease The median interval from symptom onset to confirmation of the first negative result of PCR was 16 days for patients with moderately severe disease, and 14 days for patients with mild disease The median time from symptom onset to discharge was 22 5 days for patients with moderately severe disease cases, and 16 days for patients with mild disease Some patients needed prolonged hospitalization because of persistently positive results of PCR even after remission of symptoms Comparison between the patient groups with moderately severe disease and mild disease showed that the patients with moderately severe disease were older and had higher serum ferritin and serum amyloid protein (SAA) levels than the patients with mild disease Even in patients with mild to moderate COVID-19, two to three weeks were required from symptom onset to confirmation of the first negative result of PCR, and this was one of the major factors for prolonged hospitalization The serum ferritin levels and SAA levels might be predictors of the disease severity","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89679716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.596
J. Minami, Kazutoshi Hiyama, Y. Nagasaki, N. Shimono
{"title":"A Hemodialysis Patient with COVID-19 Who Received Treatment with Hydroxychloroquine","authors":"J. Minami, Kazutoshi Hiyama, Y. Nagasaki, N. Shimono","doi":"10.11150/KANSENSHOGAKUZASSHI.94.596","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.596","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74847623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.528
Miku Oda, T. Saraya, Akinari Noda, Sunao Mikura, S. Sakuma, T. Shirai, H. Nakajima, Teppei Shimasaki, D. Kurai, T. Kamiyama, M. Kotani, Kiyoshi Moriyama, H. Tsuchiya, H. Endo, H. Kubota, T. Minamishima, K. Soejima, H. Ishii, H. Takizawa
We encountered two female patients with COVID-19 Eone transferred from the cruise ship, Diamond Princess, docked in the Yokohama port, and the other with community transmission of the infection The former patient had asymptomatic pneumonia, which subsided spontaneously The latter patient suffered from severe rapidly worsening pneumonia which necessitated mechanical ventilation and extracorporeal membrane oxygenation, but eventually showed complete resolution of the disease Although the lung involvement in those two cases at their first evaluation seemed to be equal, they exhibited very different clinical courses Eone showing self-limiting asymptomatic pneumonia and the other showing severe progressive pneumonia
{"title":"Two Cases of COVID-19 Pneumonia：One Case from the Cruise ship, Diamond Princess, and the Other, A Case of Community Transmission","authors":"Miku Oda, T. Saraya, Akinari Noda, Sunao Mikura, S. Sakuma, T. Shirai, H. Nakajima, Teppei Shimasaki, D. Kurai, T. Kamiyama, M. Kotani, Kiyoshi Moriyama, H. Tsuchiya, H. Endo, H. Kubota, T. Minamishima, K. Soejima, H. Ishii, H. Takizawa","doi":"10.11150/KANSENSHOGAKUZASSHI.94.528","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.528","url":null,"abstract":"We encountered two female patients with COVID-19 Eone transferred from the cruise ship, Diamond Princess, docked in the Yokohama port, and the other with community transmission of the infection The former patient had asymptomatic pneumonia, which subsided spontaneously The latter patient suffered from severe rapidly worsening pneumonia which necessitated mechanical ventilation and extracorporeal membrane oxygenation, but eventually showed complete resolution of the disease Although the lung involvement in those two cases at their first evaluation seemed to be equal, they exhibited very different clinical courses Eone showing self-limiting asymptomatic pneumonia and the other showing severe progressive pneumonia","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85107558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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