Evaluation of combinations of nalbuphine with acepromazine or detomidine for sedation in ponies

P. Taylor, H. Rymaszewska, S. Young
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引用次数: 10

Abstract

Summary The effect of combinations of nalbuphine (0.3 mg/kg) with either detomidine (10 μg/kg) or acepromazine (50 μg/kg) was investigated in ponies. Nalbuphine enhanced the degree of sedation produced by both sedatives; sedation with detomidine and nalbuphine was profound. Cardiovascular and respiratory effects were mild and could usually be attributed to the effect of the sedative itself. Side effects were minimal and gave no cause for concern. It was concluded that nalbuphine, in combination with acepromazine or detomidine, is a safe and effective sedative for use in ponies.
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纳布啡与乙酰丙嗪或托咪定联合用于小马镇静的评价
研究了纳布啡(0.3 mg/kg)与托托咪定(10 μg/kg)或乙酰丙嗪(50 μg/kg)联合使用对小马的影响。纳布啡增强了两种镇静剂的镇静程度;用托咪定和纳布啡进行深度镇静。心血管和呼吸系统的影响是轻微的,通常可以归因于镇静剂本身的作用。副作用很小,无需担心。结论:纳布啡与乙酰丙嗪或托咪定合用是一种安全有效的小马驹镇静剂。
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Documents Twenty-first-century perspectives Correspondence A mathematical model to describe the oxygen-haemoglobin equilibrium curve of the Thoroughbred horse Evaluation of combinations of nalbuphine with acepromazine or detomidine for sedation in ponies
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