Prooxidant-antioxidant processes in blood and liver of murine rodents (Myodes glareolus and Apodemus flavicollis) under single irradiation

IF 0.4 Q4 PHYSICS, NUCLEAR Nuclear Physics and Atomic Energy Pub Date : 2023-03-25 DOI:10.15407/jnpae2023.01.060
Yu.P. Hrynevych, L. Makovetska, A.I. Lуpska, O. Burdo
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Abstract

The effect of total single X-ray irradiation (1.5 Gy) on the course of free radical processes (FRP) in the blood and liver of red fistula (Myodes glareolus) and yellow-throated mouse (Apodemus flavicollis) was studied. It is shown that physicochemical regulation of FRP in the blood of murine rodents under total X-ray irradiation (1.5 Gy) in the early stages is carried out mainly due to catalase and reduced glutathione (GSH). This is evidenced by the stoichiometry of the CL reaction and symbat changes in the prooxidant-antioxidant ratio (PAR) and basic kinetic parameters of the CL reaction (Imax, Ifin) and antibat changes to PAR - catalase and GSH.
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单次照射下小鼠血液和肝脏的促氧化-抗氧化过程(光斑肌鼠和黄斑鼠)
研究了单次总x射线照射(1.5 Gy)对红瘘鼠(Myodes glareolus)和黄喉鼠(Apodemus flavicollis)血液和肝脏中自由基过程(FRP)的影响。结果表明,在全x射线照射(1.5 Gy)下,早期小鼠血液中玻璃钢的理化调节主要是通过过氧化氢酶和还原性谷胱甘肽(GSH)进行的。这可以从CL反应的化学计量学、促氧化-抗氧化比(PAR)和CL反应的基本动力学参数(Imax、Ifin)的显著变化以及对PAR -过氧化氢酶和GSH的抗氧化变化中得到证明。
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来源期刊
CiteScore
0.70
自引率
33.30%
发文量
10
审稿时长
19 weeks
期刊介绍: The journal Nuclear Physics and Atomic Energy presents the publications on Nuclear Physics, Atomic Energy, Radiation Physics, Radioecology, Engineering and Methods of Experiment. The journal includes peer-reviewed articles which are completed works containing new results of theoretical and experimental researches and are of interest for the scientists, postgraduate students, engineers and for the senior students.
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