Evaluation of an Add-on Local Exhaust Ventilation System for an Ethylene Oxide (ETO) Sterilizer

Abstract

Abstract An add-on local exhaust ventilation (LEV) system was evaluated as an engineering control measure during a follow-up study of high ethylene oxide (ETO) exposures at a U.S. Army medical center. Baseline breathing zone and general area samples were collected to characterize ETO exposure, and existing general ventilation was evaluated. ETO-contaminated air was recirculated back to the sterilizer area by the air-conditioning system. This recirculation, coupled with a positive differential air pressure in the sterilizer area, caused the ETO to migrate to other areas. General area sample results ranged from 0.95 to 2.80 ppm as a time-weighted average, with peak real-time exposures greater than 50 ppm. Breathing zone sample results exceeded the Occupational Safety and Health Administration action level for nine of ten individuals sampled (7 of 10 if the lower confidence limit {LCL} is applied to the sample results), with five individuals exposed to ETO concentrations greater than the PEL(3 greater than t...