Colorectal Cancer: New Perspectives

AsmaH. Qudayr, Ahmed M. Kabel, M. Abdelmaaboud, Waleed Y. Alghamdi, Amal A. Alghorabi
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引用次数: 2

Abstract

Colorectal cancer is one of the gastrointestinal malignant tumors that carries relatively poor prognosis. It represents one of the most common cancers in males and the third commonest cancer among females worldwide. Various factors may contribute to the pathogenesis of colorectal cancer such as adenomatous polyps and personal history of chronic inflammatory bowel disease. Early colorectal carcinoma is usually asymptomatic. Bleeding from the rectum is the most common presenting symptom. Intestinal obstruction and distant metastasis are life threatening complications of colorectal carcinoma. Accurate diagnosis is achieved by sampling of areas of the colon suspicious for possible tumor development during colonoscopy or sigmoidoscopy. Lines of treatment include surgery, chemotherapy, radiotherapy and biologic treatment. This review sheds light on colorectal carcinoma regarding its prevalence, etiology, clinical presentation, diagnosis and possible lines of management.
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结直肠癌:新视角
结直肠癌是一种预后较差的胃肠道恶性肿瘤。它是男性中最常见的癌症之一,也是全球女性中第三常见的癌症。多种因素可能导致结直肠癌的发病机制,如腺瘤性息肉和慢性炎症性肠病的个人病史。早期结直肠癌通常无症状。直肠出血是最常见的症状。肠梗阻和远处转移是大肠癌危及生命的并发症。在结肠镜检查或乙状结肠镜检查期间,通过对结肠可疑区域进行取样来实现准确的诊断。治疗方法包括手术、化疗、放疗和生物治疗。本文综述了结直肠癌的患病率、病因、临床表现、诊断和可能的治疗方法。
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