Microelectronic Gas sensors for Non-invasive Analysis of Exhaled Gases

Aroutiounian Vm
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Abstract

Interest in the research of small-sized gas sensors (especially semiconductor) for medical applications has sharply increased in recent years. Requirements for to such sensors are their high sensitivity, performance and stability to very low concentrations of gases, mainly exhaled by a living organism. Today the doctor not only polls, and examines the patient but also sends it to the lab-tests of blood, urine, perform an electrocardiogram, etc. But, for example, today’s periodic monitoring of glucose concentrations in the blood induces acute pain, risk of virus (e.g., hepatitis B) infection from needles, and other difficulties in frequent monitoring. Even in 1784, Antoine Lavoisier wrote that of all the phenomena of life, none is more striking and worthier for physicists and physiologists than phenomena accompanying the breath. Meanwhile, one of the most important directions of modern medicine is non-invasive diagnostics of the patient, based on the analysis of exhaled air in a special device.
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用于呼气气体无创分析的微电子气体传感器
近年来,研究用于医疗应用的小型气体传感器(特别是半导体)的兴趣急剧增加。对这类传感器的要求是对非常低浓度的气体(主要是生物体呼出的气体)具有高灵敏度、高性能和稳定性。今天,医生不仅给病人做投票和检查,而且还把病人送到实验室——验血、尿检、做心电图等等。但是,例如,今天对血液中葡萄糖浓度的定期监测会引起急性疼痛,针头感染病毒(例如乙型肝炎)的风险,以及频繁监测的其他困难。甚至在1784年,安托万·拉瓦锡(Antoine Lavoisier)就曾写道,对于物理学家和生理学家来说,在所有的生命现象中,没有什么比伴随呼吸的现象更引人注目、更有价值了。与此同时,现代医学最重要的方向之一是对病人进行无创诊断,这种诊断是基于对一种特殊装置中呼出的空气的分析。
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