PATHOGENETIC ASPECTS OF THE USE OF LASER RADIATION IN THE TREATMENT OF CHRONIC HEPATITIS

N. Burduli, A. S. Krifaridi, I. Aksenova
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引用次数: 1

Abstract

The aim of the work was to study the effect of low-intensity laser radiation on the cytokine system, vascular endothelial function in patients with chronic hepatitis. All patients were divided into three groups: in the I th (control) group (30 people) only traditional drug therapy was used for treatment, patients of the II th group (45 people) along with drug therapy received intravenous laser therapy and the III group of patients (45 people) received a course of cutaneous laser therapy. The results of our study indicate that drug therapy in patients with CG is not accompanied by a significant improvement in the plasma levels of NOx, as well as Pro-inflammatory cytokines, and the inclusion of laser therapy in the complex of therapeutic measures contributes to a significant improvement in the plasma levels of NOx, eliminating the imbalance of cytokine regulation. Various methods of laser therapy improve the NOproducing function of the endothelium, improve the functional state of the vascular endothelium, have an immunomodulatory effect. НАУЧНЫЕ ВЕДОМОСТИ | ■; | Серия: Медицина. Фармация. 2019. Том 42, No 1 5 6 НАУЧНЫЕ ВЕДОМОСТИ у Серия: Медицина. Фармация. 2019. Том 42, No 1 Ключевые слова: дисфункция эндотелия, оксид азота, цитокины, хронический гепатит, низкоинтенсивная лазерная терапия.
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应用激光辐射治疗慢性肝炎的发病机制
本研究旨在探讨低强度激光照射对慢性肝炎患者细胞因子系统、血管内皮功能的影响。所有患者分为三组:第1组(对照组)30人仅采用传统药物治疗,第2组(45人)在药物治疗的同时进行静脉激光治疗,第3组(45人)进行一个疗程的皮肤激光治疗。我们的研究结果表明,CG患者的药物治疗并没有伴随着血浆NOx水平以及促炎细胞因子水平的显著改善,而将激光治疗纳入治疗措施的复合体有助于显著改善血浆NOx水平,消除细胞因子调节的不平衡。各种激光治疗方法可提高内皮细胞的一氧化氮生成功能,改善血管内皮的功能状态,具有免疫调节作用。НАУЧНЫЕ ВЕДОМОСТИ |■;| Серия: Медицина。Фармация。2019. Том42,没有1 5 6НАУЧНЫЕВЕДОМОСТИуСерия:Медицина。Фармация。2019. Том42,没有1Ключевыеслова:дисфункцияэндотелия,оксидазота,цитокины,хроническийгепатит,низкоинтенсивнаялазернаятерапия。
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