Black Fungus an Escalating Threat for Covid-19 Patients Calling Out Captivation

Humaira Zafar, Irfan Ali Mirza, Wajid Hussain, M. Fayyaz
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Abstract

Background Current year 2021, brought a hope for the world due to availability of various vaccines to prevent COVID 19. Researchers around the Globe, kept working around the clock to dig up various correlations of this infection. So, that morbidity and mortality rates can be reduced. In all this sprint, cases of black fungus came into light in India. The Indian researchers identified strong association of black fungus co infection in COVID patients resulting in high mortality rates. Objectives Therefore, this current systematic review was planned to identify the predisposing factors, clinical presentations and management options for black fungus in COVID 19 patients. Methodology: This ‘systematic review’ was carried out following preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines & various search engines. Total 20(N) articles were selected and included for study. After following PRISMA guidelines and based upon inclusion and exclusion criteria of study, total 05 (N) manuscripts, were included. Results Out of 05(N) selected articles, 80 %( 04) strongly supported strong association of black fungus with COVID 19 patients. The highlighted predisposing factors includes, immunosuppression, anti virals, prolong hospital stay, use of tocilizumab and steroids as management of COVID patients. Timely diagnosis and provision of anti-fungal can be helpful to reduce mortality form this co infection. Conclusion It is concluded that immunosuppression, anti virals, prolong hospital stay, use of tocilizumab and steroids as management of COVID predisposes to black fungus. Timely diagnosis and use of systematic anti fungals can reduce mortality rate form this co infection.
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黑真菌对Covid-19患者的威胁不断升级,呼吁吸引
2021年,由于各种预防COVID - 19的疫苗的可用,给世界带来了希望。全球的研究人员夜以继日地工作,挖掘这种感染的各种相关性。因此,发病率和死亡率可以降低。在整个冲刺过程中,黑菌病在印度曝光。印度研究人员发现,黑真菌合并感染与COVID患者有很强的关联,导致高死亡率。因此,本系统综述旨在确定COVID - 19患者黑木耳的易感因素、临床表现和管理方案。方法:本“系统评价”是按照系统评价和元分析(PRISMA)指南和各种搜索引擎的首选报告项目进行的。共选择20(N)篇文章纳入研究。在遵循PRISMA指南并基于研究的纳入和排除标准后,总共纳入了05 (N)篇论文。结果在05篇(N篇)文章中,80%(04篇)强烈支持黑木耳与COVID - 19患者的强相关性。突出的易感因素包括免疫抑制、抗病毒药物、延长住院时间、使用托珠单抗和类固醇作为COVID患者的管理。及时诊断和提供抗真菌药物有助于降低这种合并感染的死亡率。结论免疫抑制、抗病毒药物治疗、延长住院时间、使用托珠单抗和类固醇治疗可使新冠肺炎患者易感染黑木耳。及时诊断和系统使用抗真菌药物可降低这种合并感染的死亡率。
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