Switching Hybrid Control of Blood Glucose in Diabetic Göttingen Minipigs

K. Lunze, B. Misgeld, S. Leonhardt
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Abstract

Abstract This paper presents the results of our recent blood glucose control trials with diabetic Gottingen minipigs. In particular, we describe our new switching hybrid control algorithm which uses different sampling intervals and insulin application strategies for daytime and night phases. The experimental results of the control application to two animals are given and compared with manual insulin treatment. Both strategies for glucose regulation result in comparable blood glucose trajectories even though meals were not announced to the controller but were taken into account in the manual protocol.
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糖尿病迷你猪血糖开关杂交控制Göttingen
本文介绍了我们最近对糖尿病哥廷根猪进行的血糖控制试验的结果。特别地,我们描述了一种新的开关混合控制算法,该算法在白天和夜间阶段使用不同的采样间隔和胰岛素应用策略。给出了对照应用于两只动物的实验结果,并与人工胰岛素治疗进行了比较。这两种血糖调节策略产生了相似的血糖轨迹,即使没有向控制者宣布膳食,但在手动方案中被考虑在内。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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