the formulation of the basil (Ocimum Basilicum Linn) leaf juiced ointment as a liniment

Iim Hasanah
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Abstract

Basil is traditional medicinal plants found a lot of in Indonesia. Basil leaves affication as analgetic, antiinflamantory, bacteria and antioxidant. This study aims to make an ointment stock that fulfills the requirements of preparation, knowing the physical properties of basil (Ocimum sanctum L) leaf juice. This research is an experimental research by making and evaluating basil leaves ointment preparations. The result of this research is that the juice of basil leaves (Ocimum sanctum L) containing the flavanoid compounds, tannins, and steroids and can be made as ointment stock that fulfill the requirements of physical properties evaluation. The organoleptic test included color, odor, and texture, from the three bases, it showed that the different types of basil leaf-squeezed ointment bases caused differences in the strength of the ointment preparations, while the color showed clear white and green. In the pH test, the three preparations had a pH of 5, the pH met the requirements for the pH of the topical preparation, which is between 4 – 6 which is the same as the normal pH of the skin. The homogeneity test of the three preparations showed that the preparations were homogeneous (no coarse lumps). The dispersion test has a dispersion of FI 3,5 cm, FII 5 cm, FIII 5,2 cm. Meanwhile the adhesion test is 4 seconds, 4,30 seconds, and 4,50 seconds. Keywords : Basil leaves, Evaluation tests, Ointments
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罗勒叶(Ocimum Basilicum Linn)榨汁软膏作为搽剂
罗勒是传统的药用植物,在印度尼西亚有很多。罗勒叶有止痛、消炎、抑菌和抗氧化的功效。本研究的目的是在了解罗勒叶汁的物理性质的基础上,制备符合制剂要求的软膏原液。本研究是对罗勒叶软膏制剂的制备及评价进行实验研究。本研究结果表明,罗勒叶(Ocimum sanctum L)汁含有黄酮类化合物、单宁和类固醇,可制成软膏原料,满足物理性质评价的要求。感官测试包括颜色、气味和质地,从三种基质来看,不同类型的罗勒叶挤压软膏基质导致软膏制剂的强度存在差异,而颜色呈现出清晰的白色和绿色。在pH测试中,三种制剂的pH值均为5,pH值符合外用制剂的pH值要求,在4 - 6之间,与皮肤正常pH值相同。三种制剂均质性试验表明,三种制剂均质(无粗块)。分散度试验有FII 3、5 cm、FII 5、2 cm的分散度。同时附着力测试为4秒、4秒、30秒、4秒、50秒。关键词:罗勒叶;评价试验;软膏
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