Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.132
Asa Falahi
Furosemide is a sulfonamide-derived diuretic drug which is an alternative treatment for heart failure. Furosemide was made into slow-release tablets to improve the criteria for poor furosemide and maximize its absorption in the stomach. The purpose of this study was to determine whether floating furosemide tablets with a concentration of 23% carbopol matrix could meet the requirements for evaluating the physical properties of tablets compared theoretically with the literatur. The research design used was pre-experimental. In this study, the results of the weight uniformity test showed that there were no deviations from column A and column B, tablet hardness test with an average of 5.4 kg, tablet friability test with a % friability value of 0.08%, floating lag time test with an average time of 184 seconds, and the floating duration time test is with an average time of 8 hours. From the research data, it can be concluded that the floating furosemide tablet with a carbopol matrix concentration of 23% fulfills all evaluations of the physical properties of the tablet
{"title":"EVALUASI SIFAT FISIK TABLET FLOATING FUROSEMIDE DENGAN MATRIKS CARBOPOL","authors":"Asa Falahi","doi":"10.53864/jifakfar.v6i1.132","DOIUrl":"https://doi.org/10.53864/jifakfar.v6i1.132","url":null,"abstract":"Furosemide is a sulfonamide-derived diuretic drug which is an alternative treatment for heart failure. Furosemide was made into slow-release tablets to improve the criteria for poor furosemide and maximize its absorption in the stomach. The purpose of this study was to determine whether floating furosemide tablets with a concentration of 23% carbopol matrix could meet the requirements for evaluating the physical properties of tablets compared theoretically with the literatur. The research design used was pre-experimental. In this study, the results of the weight uniformity test showed that there were no deviations from column A and column B, tablet hardness test with an average of 5.4 kg, tablet friability test with a % friability value of 0.08%, floating lag time test with an average time of 184 seconds, and the floating duration time test is with an average time of 8 hours. From the research data, it can be concluded that the floating furosemide tablet with a carbopol matrix concentration of 23% fulfills all evaluations of the physical properties of the tablet","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91114299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.122
D. Nurmalasari
Acne is a skin disease disorder that is often experienced by some people, excess oil on the skin can cause infection and inflammation caused by the development of acne bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes. The purpose of this study was to determine the effect of variations in KOH concentration on the physical properties of papaya leaf extract liquid soap preparations (Carica papaya L.). The research design used was a pre-experimental research design with one group post-design, using research objects as many as 3 sample treatment groups (variations in KOH concentration 14%; 16%; 18%) as sample research objects. The results of organoleptic tests show that variations in KOH concentration affect the physical properties of organoleptic, texture, and aroma. The homogeneity test results of the three formulas show homogeneous results. The results of the pH test using statistical tests using the One Way ANOVA method obtained a significant value of 0.000 (p-value 0.05). The viscosity test results using the One Way ANOVA method obtained a significant value of 0.000 (p value0.05). The results of the foam height test using the One Way ANOVA method obtained a significant value of 0.006 (p value0.05). Based on the research that has been done, it can be concluded that KOH affects the physical properties of soap, namely organoleptic tests, pH, viscosity, and foam height. Keywords: Liquid Soap, Potassium Hydroxide, Physical Properties
痤疮是一些人经常会经历的一种皮肤病紊乱，皮肤上过多的油脂会引起感染和炎症，导致痤疮细菌如金黄色葡萄球菌、表皮葡萄球菌、痤疮丙酸杆菌等的发展。本研究的目的是确定KOH浓度的变化对木瓜叶提取物液体皂制剂(Carica papaya L.)物理性质的影响。采用的研究设计为实验前研究设计和一组后设计，研究对象多达3个样本处理组(KOH浓度变化14%;16%;18%)作为样本研究对象。感官测试结果表明，KOH浓度的变化影响了感官、质地和香气的物理性质。三种公式的均匀性检验结果均为均匀性。采用单因素方差分析(One Way ANOVA)方法进行统计检验，pH值的显著性值为0.000 (p值0.05)。采用单向方差分析(One Way ANOVA)方法进行黏度检验，得到显著值0.000 (p值0.05)。泡沫高度检验的单因素方差分析(One Way ANOVA)得到显著值0.006 (p值0.05)。根据所做的研究，可以得出结论，KOH影响肥皂的物理性能，即感官测试、pH值、粘度和泡沫高度。关键词:液体皂，氢氧化钾，物理性质
{"title":"PENGARUH VARIASI KONSENTRASI KOH TERHADAP SIFAT FISIK SABUN CAIR EKSTRAK DAUN PEPAYA (Carica papaya L.)","authors":"D. Nurmalasari","doi":"10.53864/jifakfar.v6i1.122","DOIUrl":"https://doi.org/10.53864/jifakfar.v6i1.122","url":null,"abstract":"Acne is a skin disease disorder that is often experienced by some people, excess oil on the skin can cause infection and inflammation caused by the development of acne bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes. The purpose of this study was to determine the effect of variations in KOH concentration on the physical properties of papaya leaf extract liquid soap preparations (Carica papaya L.). The research design used was a pre-experimental research design with one group post-design, using research objects as many as 3 sample treatment groups (variations in KOH concentration 14%; 16%; 18%) as sample research objects. The results of organoleptic tests show that variations in KOH concentration affect the physical properties of organoleptic, texture, and aroma. The homogeneity test results of the three formulas show homogeneous results. The results of the pH test using statistical tests using the One Way ANOVA method obtained a significant value of 0.000 (p-value 0.05). The viscosity test results using the One Way ANOVA method obtained a significant value of 0.000 (p value0.05). The results of the foam height test using the One Way ANOVA method obtained a significant value of 0.006 (p value0.05). Based on the research that has been done, it can be concluded that KOH affects the physical properties of soap, namely organoleptic tests, pH, viscosity, and foam height. Keywords: Liquid Soap, Potassium Hydroxide, Physical Properties","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75610786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.137
Kukuh Handojo
This research aims to analyze product quality in Traditional Medicine Micro Businesses in Purwoharjo District and Srono District whether it is under control or not under control and to find the cause of product damage (defects) of the Traditional Medicine Micro Business. In this study the analysis method used is Statistical Quality Control, which is a statistical method used to solve problems used to analyze, improve products and processes using statistical methods. This research is a type of quantitative research using data collection techniques through observation, interviews, and documentation. Data collection uses a retrospective method. The data analysis used is check sheet, control diagram, and pareto diagram. The results of this study indicate that product quality control at UMOT is still not under control, with an average damage to UMOT A liquid jamu of 3.34% in 3 months, UMOT B liquid jamu of 45% in 3 months, and UMOT C liquid jamu of 41% in 3 months. The most common type of damage was shrunken packaging with 123 bottles of liquid jamu UMOT C and 120 bottles of liquid jamu UMOT B in 3 months, October-December 2022. From the results of observations and interviews in the field, the factors that cause the damage are: the material is a used bottle.
{"title":"ANALISIS KUALITAS PRODUK MENGGUNAKAN METODE STATISTICAL QUALITY CONTROL PADA USAHA MIKRO OBAT TRADISIONAL DI BANYUWANGI","authors":"Kukuh Handojo","doi":"10.53864/jifakfar.v6i1.137","DOIUrl":"https://doi.org/10.53864/jifakfar.v6i1.137","url":null,"abstract":"This research aims to analyze product quality in Traditional Medicine Micro Businesses in Purwoharjo District and Srono District whether it is under control or not under control and to find the cause of product damage (defects) of the Traditional Medicine Micro Business. In this study the analysis method used is Statistical Quality Control, which is a statistical method used to solve problems used to analyze, improve products and processes using statistical methods. This research is a type of quantitative research using data collection techniques through observation, interviews, and documentation. Data collection uses a retrospective method. The data analysis used is check sheet, control diagram, and pareto diagram. The results of this study indicate that product quality control at UMOT is still not under control, with an average damage to UMOT A liquid jamu of 3.34% in 3 months, UMOT B liquid jamu of 45% in 3 months, and UMOT C liquid jamu of 41% in 3 months. The most common type of damage was shrunken packaging with 123 bottles of liquid jamu UMOT C and 120 bottles of liquid jamu UMOT B in 3 months, October-December 2022. From the results of observations and interviews in the field, the factors that cause the damage are: the material is a used bottle.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78283109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.136
Dewi - Rashati
Solid soaps are the most commonly used. The addition of various concentrations of Cocamide DEA is expected to fulfill the physical properties test of solid bath soap. The purpose of this study was to determine the effect of variations in the concentration of Cocamide DEA on the physical properties of solid soap. knowing how many concentrations of Cocamide Dea formulation that meet the physical properties test of solid soap. a pre-experimental (one group) post-test design was used for this research method. The ingredients used in this study were cocamide DEA, NaOH, purple sweet potato extract, 70% ethanol, olive oil, coconut oil, chewing gum fragrance, aquadest. The treatments in this study were various concentrations of Cocamide DEA F1 2%, F2 3%, F3 5%. Parameters observed were organoleptic test, pH test, water content test, foam height test. organoleptic results showed that F1, F2, F3 had a smooth texture, a strong bubble gum aroma, F1 was dark brown, F2 was brown, F3 was light brown. Results pH F1 9.4, F2 9.6 F3 9.8. The results of the water content of F1 0.02%, F2 0.03% F3 0.07%. High yield foam F1 7.0, F2 7.4, F3 7.8. Cocamide DEA with a concentration of 2% F1 which meets the physical properties test of solid soap.
固体肥皂是最常用的。不同浓度的Cocamide DEA的加入有望满足固体沐浴皂的物理性能测试。本研究的目的是确定Cocamide DEA浓度的变化对固体肥皂物理性能的影响。知道有多少浓度的Cocamide Dea配方符合固体肥皂的物理性能测试。本研究方法采用实验前(一组)后测设计。本研究的主要成分为:可可酰胺DEA、NaOH、紫甘薯提取物、70%乙醇、橄榄油、椰子油、口香糖香精、aquadest。本研究采用不同浓度的Cocamide DEA F1 2%， F2 3%， f35 5%处理。观察参数为感官试验、pH试验、含水量试验、泡沫高度试验。感官结果表明，F1、F2、F3质地光滑，泡泡糖香气浓厚，F1为深棕色，F2为棕色，F3为浅棕色。结果pH F1为9.4,F2为9.6,F3为9.8。结果F1的含水量为0.02%，F2为0.03%，F3为0.07%。高产泡沫F1 7.0, F2 7.4, F3 7.8。Cocamide DEA的浓度为2% F1，满足固体肥皂的物理性能测试。
{"title":"THE EFFECT OF DEA COCAMIDE CONCENTRATION VARIATIONS ON PHYSICAL PROPERTIES OF PURPLE SWEET (Ipomea batatas L.) EXTRACT SOLID SOAP PREPARATIONS","authors":"Dewi - Rashati","doi":"10.53864/jifakfar.v6i1.136","DOIUrl":"https://doi.org/10.53864/jifakfar.v6i1.136","url":null,"abstract":"Solid soaps are the most commonly used. The addition of various concentrations of Cocamide DEA is expected to fulfill the physical properties test of solid bath soap. The purpose of this study was to determine the effect of variations in the concentration of Cocamide DEA on the physical properties of solid soap. knowing how many concentrations of Cocamide Dea formulation that meet the physical properties test of solid soap. a pre-experimental (one group) post-test design was used for this research method. The ingredients used in this study were cocamide DEA, NaOH, purple sweet potato extract, 70% ethanol, olive oil, coconut oil, chewing gum fragrance, aquadest. The treatments in this study were various concentrations of Cocamide DEA F1 2%, F2 3%, F3 5%. Parameters observed were organoleptic test, pH test, water content test, foam height test. organoleptic results showed that F1, F2, F3 had a smooth texture, a strong bubble gum aroma, F1 was dark brown, F2 was brown, F3 was light brown. Results pH F1 9.4, F2 9.6 F3 9.8. The results of the water content of F1 0.02%, F2 0.03% F3 0.07%. High yield foam F1 7.0, F2 7.4, F3 7.8. Cocamide DEA with a concentration of 2% F1 which meets the physical properties test of solid soap.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78400325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.129
Agnis Pondinekaria Aditama
Skin disease is a disease that attacks the surface of the body caused by various causes such as fungi, bacteria and parasites. Skin diseases can be treated by self-medication. The research location was carried out at RT 04 Gondoruso Village, Pasirian District. The aim of this research to know of describing skin disease self-medication in RT 04 of the Gondoruso village community. Data collection was carried out using a survey method and using a questionnaire as a data collection tool. The data collection procedure was carried out by giving questionnaires to respondents by visiting the respondent's house directly. This type of research is quantitative descriptive with 72 respondents. The instruments used in this study were questionnaires and data collection sheets (LPD). Based on the results of the study, it can be concluded that the description of the community in RT 04 Gondoruso Village, Pasirian District, Lumajang Regency shows good category knowledge about self-medication using skin disease drugs. This is shown from the percentage value of knowledge about skin diseases of 89.72% and about the use of drugs for skin diseases of 97,22% Keywords: Knowledge, Skin Disease, Self-medication.
{"title":"GAMBARAN PENGETAHUAN MASYARAKAT TENTANG SWAMEDIKASI PENGGUNAAN OBAT PENYAKIT KULIT DI RT 04 DESA GONDORUSO KECAMATAN PASIRIAN KABUPATEN LUMAJANG","authors":"Agnis Pondinekaria Aditama","doi":"10.53864/jifakfar.v6i1.129","DOIUrl":"https://doi.org/10.53864/jifakfar.v6i1.129","url":null,"abstract":"Skin disease is a disease that attacks the surface of the body caused by various causes such as fungi, bacteria and parasites. Skin diseases can be treated by self-medication. The research location was carried out at RT 04 Gondoruso Village, Pasirian District. The aim of this research to know of describing skin disease self-medication in RT 04 of the Gondoruso village community. Data collection was carried out using a survey method and using a questionnaire as a data collection tool. The data collection procedure was carried out by giving questionnaires to respondents by visiting the respondent's house directly. This type of research is quantitative descriptive with 72 respondents. The instruments used in this study were questionnaires and data collection sheets (LPD). Based on the results of the study, it can be concluded that the description of the community in RT 04 Gondoruso Village, Pasirian District, Lumajang Regency shows good category knowledge about self-medication using skin disease drugs. This is shown from the percentage value of knowledge about skin diseases of 89.72% and about the use of drugs for skin diseases of 97,22% Keywords: Knowledge, Skin Disease, Self-medication.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91084068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.133
Rosida Hari
Papaya leaves have a number of alkaloid compounds (carpaine, pseudocarpaine, dehydrocarpaine I, dehydrocapaine II and emetine. Carpaine is piperidin alkaloid. The piperidin alkaloid have activity of antiplatelet. This study aims to determine the antiplatelet activity of papaya leaf extract againts male mice. Desain of this research is pure experimental research with pre test – post test control group design. Subjects consisted of 4 groups of mice each group consisted of 5 mice. This study was devided into 4 groups : negative control CMC Na 1%, papaya leaf extract (Carica papaya L) concentration 10%/30g BB, papaya leaf extract (Carica papaya L) 25%/30g BB and papaya leaf extract (Carica papaya L) 50%/30g BB. Method of determined antiplatelet based on parameters using the tail bleeding time. Then the time bleeding was determind on day 0 and day 7. After the percentage increase of bleeding time stastical data were analyzed by one way analysis of variance (ANOVA). The results showed that the yield of papaya leaf extract was 17.6% with 96% ethanol solvent.Research result was found bleeding time with percentage of successive increase in extract papaya leaf 10% (84,33),extract papaya leaf 25% (157,70) and papaya leaf extract 50% (177,53). The result of data analysis using one way anova showed the difference between bleeding time and the value (sig F=0,000). This result showed a significant difference between treatment groups.
{"title":"ANTIPLATELET ACTIVITY OF PAPAYA LEAF EXTRACT (Carica papaya L) IN MICE","authors":"Rosida Hari","doi":"10.53864/jifakfar.v6i1.133","DOIUrl":"https://doi.org/10.53864/jifakfar.v6i1.133","url":null,"abstract":"Papaya leaves have a number of alkaloid compounds (carpaine, pseudocarpaine, dehydrocarpaine I, dehydrocapaine II and emetine. Carpaine is piperidin alkaloid. The piperidin alkaloid have activity of antiplatelet. This study aims to determine the antiplatelet activity of papaya leaf extract againts male mice. Desain of this research is pure experimental research with pre test – post test control group design. Subjects consisted of 4 groups of mice each group consisted of 5 mice. This study was devided into 4 groups : negative control CMC Na 1%, papaya leaf extract (Carica papaya L) concentration 10%/30g BB, papaya leaf extract (Carica papaya L) 25%/30g BB and papaya leaf extract (Carica papaya L) 50%/30g BB. Method of determined antiplatelet based on parameters using the tail bleeding time. Then the time bleeding was determind on day 0 and day 7. After the percentage increase of bleeding time stastical data were analyzed by one way analysis of variance (ANOVA). The results showed that the yield of papaya leaf extract was 17.6% with 96% ethanol solvent.Research result was found bleeding time with percentage of successive increase in extract papaya leaf 10% (84,33),extract papaya leaf 25% (157,70) and papaya leaf extract 50% (177,53). The result of data analysis using one way anova showed the difference between bleeding time and the value (sig F=0,000). This result showed a significant difference between treatment groups.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75241763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.119
Ni Nyoman Ratih Diana Utari
Banyak faktor yang dapat menyebabkan munculnya jerawat, yang mana sejak dulu jerawat selalu menjadi permasalahan utama pada kulit terutama bagi orang yang memiliki kulit sensitif. Beruntungnya salah satu tanaman herbal di indonesia yang di jadikan obat herbal secara turun temurun yaitu Pegagan (Centella asiatica (L.) Urban) yang merupakan tanaman liar dapat di olah juga sebagai obat dalam mengatasi jerawat karena memiliki antibakteri di dalamnya. Dan dengan menggunakan metode literatur jurnal, maka peneliti mencari 20 jurnal yang memiliki kesamaan fokus penelitian, yang mana selanjutnya di saring menjadi 5 jurnal yang paling mendekati fokus penelitian. Dan hasil yang di dapatkan setelah menganalisis jurnal-jurnal tersebut memperlohatkan bahwa herbal pegagan memiliki efek yang bagus bagi kulit sehingga bisa di ektrak dan di gunakan pada kulit yang berjerawat. Setiap jurnal memiliki permasaan serta perbedaan yang sesuai dengan fokus penelitian yang di tetapkan oleh para peneliti.
{"title":"LITERATURE REVIEW: EKSTRAK DAUN PEGEGAN SEBAGAI ANTI JERAWAT","authors":"Ni Nyoman Ratih Diana Utari","doi":"10.53864/jifakfar.v6i1.119","DOIUrl":"https://doi.org/10.53864/jifakfar.v6i1.119","url":null,"abstract":"Banyak faktor yang dapat menyebabkan munculnya jerawat, yang mana sejak dulu jerawat selalu menjadi permasalahan utama pada kulit terutama bagi orang yang memiliki kulit sensitif. Beruntungnya salah satu tanaman herbal di indonesia yang di jadikan obat herbal secara turun temurun yaitu Pegagan (Centella asiatica (L.) Urban) yang merupakan tanaman liar dapat di olah juga sebagai obat dalam mengatasi jerawat karena memiliki antibakteri di dalamnya. Dan dengan menggunakan metode literatur jurnal, maka peneliti mencari 20 jurnal yang memiliki kesamaan fokus penelitian, yang mana selanjutnya di saring menjadi 5 jurnal yang paling mendekati fokus penelitian. Dan hasil yang di dapatkan setelah menganalisis jurnal-jurnal tersebut memperlohatkan bahwa herbal pegagan memiliki efek yang bagus bagi kulit sehingga bisa di ektrak dan di gunakan pada kulit yang berjerawat. Setiap jurnal memiliki permasaan serta perbedaan yang sesuai dengan fokus penelitian yang di tetapkan oleh para peneliti.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91225918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.53864/jifakfar.v6i1.135
Efyn Novianti Putri, Amaliyah Nurul Hidayah, A. P. Aditama, Anies Rohman Dwijayanti
Kalsium karbonat (CaCO3) merupakan salah satu komponen penyusun dalam pembuatan pasta gigi yang diduga berpotensi sebagai antibakteri penghambat pertumbuhan Streptococcus mutans di dalam mulut. Kalsium karbonat tersusun atas banyak mineral, salah satunya adalah kalsium oksida (CaO) yang memiliki aktivitas antimikroba. Tujuan dari penelitian ini adalah untuk mengetahui kadar CaCO3 tepung cangkang keong sawah (Pila ampullacea) dan kemampuan pasta tepung cangkang keong sawah sebagai antibakteri Streptococcus mutans. Aktivitas antibakteri pasta tepung cangkang keong sawah diuji dengan difusi cakram Kirby-Bauer terhadap Streptococcus mutans dan kadar CaCO3 diukur menggunakan titrasi alkalimetri. Amoxicillin digunakan sebagai kontrol pembanding antibakteri. Berdasarkan hasil penelitian didapatkan hasil bahwa tepung cangkang keong mengandung CaCO3 dengan kadar 28,9±0,70%. Hasil uji antibakteri menunjukkan bahwa pada konsentrasi 30%, 40%, dan 50% tidak terbentuk zona bening, sementara hanya amoxicillin sebagai antibiotik pembanding dapat membentuk zona bening (8 mm). Hasil penelitian ini menunjukkan bahwa CaCO3 yang terkandung dalam tepung cangkang keong berfungsi sebagai bahan abrasif pasta gigi. Dapat disimpulkan bahwa kadar CaCO3 dalam tepung cangkang keong sawah sebesar 28,9±0,70% dandalam sediaan pasta tidak memiliki aktifitas antibakteri terhadap Streptococcus mutans.Kata kunci : Kadar CaCO3, antibakteri , Streptococcus mutans, tepung cangkang keong sawah, pasta
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Obat kumur adalah cairan yang digunakan untuk membilas rongga mulut dengan tujuan untuk menghilangkan atau menghancurkan bakteri dan menghasilkan efek terapeutik dengan menghilangkan infeksi atau mencegah karies gigi. Daun asam jawa (Tamarindus indica L.) memiliki kandungan senyawa flavonoid dan tanin yang berfungsi sebagai anti bakteri pada rongga mulut. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi gliserin terhadap sifat fisik sediaan obat kumur daun asam jawa. Obat kumur daun asam jawa dibuat dalam 3 formula dengan konsentrasi gliserin yang berbeda-beda yaitu F1 (10%), F2 (15%), dan F3(20%). Uji sifat fisik yang dilakukan meliputi uji organoleptis, pH, dan viskositas. Hasil penelitian menunjukan bahwa sediaan obat kumur pada ketiga formula memiliki warna kuning, rasa agak manis, dan bau khas mint. pH sediaan F1 sebesar 6,20±0,10, F2 sebesar 6,16±0,15 dan F3 sebesar 6,16±0,20. Viskositas sediaan F1 sebesar 1,47±0,04 cPs, F2 sebesar 1,49±0,04 cPs dan F3 sebesar 1,55±0,01 cPs. Kesimpulan dari penelitian ini adalah variasi konsentrasi gliserin tidak berpengaruh terhadap organoleptis, pH dan viskositas sediaan obat kumur daun asam jawa.
{"title":"PENGARUH VARIASI KONSENTRASI GLISERIN SEBAGAI HUMEKTAN TERHADAP SIFAT FISIK SEDIAAN OBAT KUMUR DAUN ASAM JAWA (Tamarindus indica L.)","authors":"Mikhania Christiningtyas Eryani, Agnis Pondinekaria Aditama","doi":"10.53864/jifakfar.v5i2.105","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i2.105","url":null,"abstract":"Obat kumur adalah cairan yang digunakan untuk membilas rongga mulut dengan tujuan untuk menghilangkan atau menghancurkan bakteri dan menghasilkan efek terapeutik dengan menghilangkan infeksi atau mencegah karies gigi. Daun asam jawa (Tamarindus indica L.) memiliki kandungan senyawa flavonoid dan tanin yang berfungsi sebagai anti bakteri pada rongga mulut. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi gliserin terhadap sifat fisik sediaan obat kumur daun asam jawa. Obat kumur daun asam jawa dibuat dalam 3 formula dengan konsentrasi gliserin yang berbeda-beda yaitu F1 (10%), F2 (15%), dan F3(20%). Uji sifat fisik yang dilakukan meliputi uji organoleptis, pH, dan viskositas. Hasil penelitian menunjukan bahwa sediaan obat kumur pada ketiga formula memiliki warna kuning, rasa agak manis, dan bau khas mint. pH sediaan F1 sebesar 6,20±0,10, F2 sebesar 6,16±0,15 dan F3 sebesar 6,16±0,20. Viskositas sediaan F1 sebesar 1,47±0,04 cPs, F2 sebesar 1,49±0,04 cPs dan F3 sebesar 1,55±0,01 cPs. Kesimpulan dari penelitian ini adalah variasi konsentrasi gliserin tidak berpengaruh terhadap organoleptis, pH dan viskositas sediaan obat kumur daun asam jawa.","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84708331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-10DOI: 10.53864/jifakfar.v5i2.115
I. Iswandi
Pneumonia is an infection at the ends of the bronchioles and alveoli which causes acute inflammation of the lung parenchyma caused by various pathogens such as bacteria, fungi, viruses and parasites. Most are caused by bacteria. Inappropriate use of antibiotics can lead to increased resistance, wasted costs and does not achieve optimal clinical benefits in the prevention and treatment of infections and bacterial resistance to drugs. The purpose of this study was to determine the suitability of the use of antibiotics according to therapy with the American Thoracic Society/Infectious Diseases Society of America (ATS/IDSA) guidelines. This research method is a type of descriptive non-experimental research with a retrospective approach using cross sectional. Data collection according to the prescription of inpatients at dr. Gondo Suwarno who received antibiotics. Then grouped by type of antibiotic, dose, class, and duration of antibiotic administration. The number of samples is 100. Then the data is adjusted between therapy and guidelines. Based on the results of the study, it was found that there were more male patients. The most widely used dosage form is injection. The most common class of antibiotics is the cephalosporin group. In CAP pneumonia, the number of patients was 46 with the accuracy of the type of drug levofloxacin as many as 12 (26.08%). In HAP pneumonia, the number of patients was 54, with the accuracy of the type of antibiotic levofloxacin in 16 (29.62%). The accuracy of the type of ceftriaxone drug was 22 (40.74%)
{"title":"POLA PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA RAWAT INAP DI RSUD dr. GONDO SUWARNO TAHUN 2021","authors":"I. Iswandi","doi":"10.53864/jifakfar.v5i2.115","DOIUrl":"https://doi.org/10.53864/jifakfar.v5i2.115","url":null,"abstract":"Pneumonia is an infection at the ends of the bronchioles and alveoli which causes acute inflammation of the lung parenchyma caused by various pathogens such as bacteria, fungi, viruses and parasites. Most are caused by bacteria. Inappropriate use of antibiotics can lead to increased resistance, wasted costs and does not achieve optimal clinical benefits in the prevention and treatment of infections and bacterial resistance to drugs. The purpose of this study was to determine the suitability of the use of antibiotics according to therapy with the American Thoracic Society/Infectious Diseases Society of America (ATS/IDSA) guidelines. This research method is a type of descriptive non-experimental research with a retrospective approach using cross sectional. Data collection according to the prescription of inpatients at dr. Gondo Suwarno who received antibiotics. Then grouped by type of antibiotic, dose, class, and duration of antibiotic administration. The number of samples is 100. Then the data is adjusted between therapy and guidelines. Based on the results of the study, it was found that there were more male patients. The most widely used dosage form is injection. The most common class of antibiotics is the cephalosporin group. In CAP pneumonia, the number of patients was 46 with the accuracy of the type of drug levofloxacin as many as 12 (26.08%). In HAP pneumonia, the number of patients was 54, with the accuracy of the type of antibiotic levofloxacin in 16 (29.62%). The accuracy of the type of ceftriaxone drug was 22 (40.74%)","PeriodicalId":17737,"journal":{"name":"JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83877810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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