Ingrown toenails treatment in diabetic patients: a Pilot Study of a new conservative treatment of orthonyxia.

Cassano Vito Michele, Parra Cecilia, Griguoli Francesca, Bonino Giovanni, Di Carlo Alberto
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Abstract

Ingrown toenail (also onychocryptosis) is one of the most frequent nail pathologies in diabetic population. Neurological and vascular complications can increase painful symptoms and suffering of tissue which can lead to ulceration, therefore surgical matricectomy is not recommended. In this research we aim to evaluate the effectiveness of a 40% urea cream treatment associated whit nail acrylic resin brace (ortonixia) versus traditional cut and resin nail’s recostruction. Diameter of nail and NRS scale were used to evaluate change of nail plate and pain before and after treatment. 32 subjects with 52 treated nails were included. About 20 nails of 13 subject were recruited in experimental group. Differential final and initial diameter was 4.67±1,55 mm in experimental group and 3.01±1.26 mm in control group ( p<0.0001) and recurrence rate was 15% and 75% respectively ( p<0.0001). Also days of absence of pain, in experimental group there was a mean of 319.05±113.18 days, instead in control group there was a mean of 208.31±119.84 days (p<0.0002). This statistical analysis shows that effectiveness of new conservative approach is greater than in nail reconstruction method and a valid alternative to surgical treatment in diabetic patients.
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糖尿病患者内生趾甲治疗:一种新的保守治疗方法的初步研究。
内生趾甲是糖尿病人群中最常见的趾甲病变之一。神经和血管并发症可增加疼痛症状和组织的痛苦,可导致溃疡,因此不建议手术基质切除术。在这项研究中,我们的目的是评估40%尿素乳膏治疗与白色指甲丙烯酸树脂支架(ortonixia)相比传统切割和树脂指甲重建的有效性。采用甲直径及NRS量表评价治疗前后甲板变化及疼痛程度。纳入32名受试者,52根处理过的指甲。实验组13例,取20枚左右。试验组末初径差为4.67±1.55 mm,对照组为3.01±1.26 mm (p<0.0001),复发率分别为15%和75% (p<0.0001)。无痛天数,实验组平均为319.05±113.18天,对照组平均为208.31±119.84天(p<0.0002)。统计分析表明新保守入路的有效性大于甲重建术,是糖尿病患者手术治疗的有效替代方法。
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