V. Alfano, Gianluca Granato, Antonello Mascolo, Salvatore Tortora, Luca Basso, Antonio Farriciello, Paolo Coppola, Michele Manfredonia, Fabrizio Toro, Alfredo Tarallo, Giovanni Moggio
Neuroimaging with Magnetic Resonance Imaging (MRI) is one of the most useful tools available to study the human brain in vivo. Several techniques provide insights into the human brain's structure, function, and connectivity. The aim of this study is to showcase the feasibility of employing advanced neuroimaging techniques within the clinical routine in a patient with a neurological disorder. An 83 years-old male patient with right motor aphasia and somatosensory impairment underwent a clinical and advanced neuroimaging MRI protocol with 3D-T1, FLAIR, diffusion-weighted and tensor imaging, and resting state functional MRI. Advanced neuroimaging post-processing was employed to perform cortical and subcortical brain segmentation, white matter fibers tractography, and functional connectivity (FC). These analyses revealed an impairment of the left posterior insular cortex that showed low cortical grey matter volume, high restriction in diffusivity maps, and an increased FC as a compensation mechanism. The results pointed towards a left insular cortex stroke and the patient was then admitted to neurology for hospitalization. This amalgamation of cutting-edge technology with clinical practice underscores the pivotal role of neuroimaging in the contemporary management of neurological disorders, heralding a new era of precision medicine tailored to individual patient profiles.
利用磁共振成像(MRI)进行神经成像是研究活体人脑最有用的工具之一。有几种技术可以深入了解人脑的结构、功能和连接性。本研究旨在展示在临床常规工作中对神经系统疾病患者采用先进神经成像技术的可行性。一位 83 岁的男性患者患有右侧运动性失语症和躯体感觉障碍,他接受了临床和先进的神经成像 MRI 方案,包括 3D-T1 、FLAIR、弥散加权和张量成像以及静息状态功能 MRI。先进的神经成像后处理技术用于进行皮层和皮层下脑分割、白质纤维束成像和功能连接(FC)。这些分析表明,左侧后部岛叶皮层受损,显示出皮层灰质体积低、扩散图限制高以及作为补偿机制的 FC 增加。结果表明患者左侧岛叶皮质中风,随后患者被送入神经内科住院治疗。这项尖端技术与临床实践的结合,凸显了神经成像技术在当代神经系统疾病治疗中的关键作用,预示着根据患者个体情况量身定制精准医疗的新时代即将到来。
{"title":"Advanced neuroimaging techniques in the clinical routine: A comprehensive MRI case study","authors":"V. Alfano, Gianluca Granato, Antonello Mascolo, Salvatore Tortora, Luca Basso, Antonio Farriciello, Paolo Coppola, Michele Manfredonia, Fabrizio Toro, Alfredo Tarallo, Giovanni Moggio","doi":"10.36017/jahc202462336","DOIUrl":"https://doi.org/10.36017/jahc202462336","url":null,"abstract":"Neuroimaging with Magnetic Resonance Imaging (MRI) is one of the most useful tools available to study the human brain in vivo. Several techniques provide insights into the human brain's structure, function, and connectivity. The aim of this study is to showcase the feasibility of employing advanced neuroimaging techniques within the clinical routine in a patient with a neurological disorder. An 83 years-old male patient with right motor aphasia and somatosensory impairment underwent a clinical and advanced neuroimaging MRI protocol with 3D-T1, FLAIR, diffusion-weighted and tensor imaging, and resting state functional MRI. Advanced neuroimaging post-processing was employed to perform cortical and subcortical brain segmentation, white matter fibers tractography, and functional connectivity (FC). These analyses revealed an impairment of the left posterior insular cortex that showed low cortical grey matter volume, high restriction in diffusivity maps, and an increased FC as a compensation mechanism. The results pointed towards a left insular cortex stroke and the patient was then admitted to neurology for hospitalization. This amalgamation of cutting-edge technology with clinical practice underscores the pivotal role of neuroimaging in the contemporary management of neurological disorders, heralding a new era of precision medicine tailored to individual patient profiles.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"114 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140680536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma Scarfato, Stefania Stile, Vincenzo Maiello, Giuseppe De Feo
Photon-counting Computed Tomography (PCCT) is a new computed tomography detection technology that uses photon-counting detectors to convert individual X-ray photons directly into an electrical signal and has the potential to overcome limitations of previous CT systems, such as limited spatial resolution, or lack of spectral information. The upcoming development in PCCT technology promises to enhance image resolution, contrast, and diagnostic accuracy while reducing radiation doses to patients. In this review article, we aim to evaluate the basic principles and potential clinical benefits of PCCT, with particular attention to the constantly evolving recent literature and the changes that this method will meticulously bring to the world of cardiovascular and neuroradiological diagnostic imaging.
光子计数计算机断层扫描(PCCT)是一种新型计算机断层扫描检测技术,它使用光子计数探测器将单个 X 射线光子直接转换为电信号,有望克服以往 CT 系统的局限性,如空间分辨率有限或缺乏光谱信息等。PCCT 技术的发展有望提高图像分辨率、对比度和诊断准确性,同时减少对患者的辐射剂量。在这篇综述文章中,我们旨在评估 PCCT 的基本原理和潜在临床优势,尤其关注不断发展的最新文献,以及这种方法将为心血管和神经放射诊断成像领域带来的细致变化。
{"title":"The revolution of photon-counting CT towards new horizons of diagnostic imaging","authors":"Emma Scarfato, Stefania Stile, Vincenzo Maiello, Giuseppe De Feo","doi":"10.36017/jahc202462333","DOIUrl":"https://doi.org/10.36017/jahc202462333","url":null,"abstract":"Photon-counting Computed Tomography (PCCT) is a new computed tomography detection technology that uses photon-counting detectors to convert individual X-ray photons directly into an electrical signal and has the potential to overcome limitations of previous CT systems, such as limited spatial resolution, or lack of spectral information. The upcoming development in PCCT technology promises to enhance image resolution, contrast, and diagnostic accuracy while reducing radiation doses to patients. In this review article, we aim to evaluate the basic principles and potential clinical benefits of PCCT, with particular attention to the constantly evolving recent literature and the changes that this method will meticulously bring to the world of cardiovascular and neuroradiological diagnostic imaging.\u0000 ","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":" 58","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140683313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Filoso, Ivana Citro, M. R. Iacolare, Ida Monti, Nunzio Quinto, Giacomo Russo, Attilio Tortora, Lucio Marcello Falconio
In the year 2019, 121 patients were admitted to the Casavatore Hospice. All patients, upon admission, exhibited pressure ulcers (Ldp) in both stages I and II. A portion of the patients with stage II ulcers were treated with advanced dressings containing micronized silver (20 patients), resulting in a regression of the ulcer to stage I. Subsequently, they were treated with topical application of silver sulfadiazine cream until complete healing of the lesion. Patients who did not have favorable indications for the application of such treatment were treated with Sofargen cream (60 patients), nonetheless preventing the worsening of the stage of the pressure ulcer. Patients with stage I ulcers (41 patients) were treated daily with silver sulfadiazine spray, which still contributed to the prevention of secondary lesions associated with immobility. The objective of managing pressure ulcers in bedridden or terminal patients has been fully achieved within dignified care times and, above all, with reduced company costs. As a final result, considering the current prices for both dressings and the specific drug, we achieved an economic savings exceeding 35%, highlighting how it is possible to implement, in various aspects and situations, important yet simple care approaches while respecting therapeutic appropriateness and patient compliance.
2019 年,卡萨瓦托里安宁疗护中心收治了 121 名患者。所有患者入院时都出现了 I 期和 II 期压迫性溃疡(Ldp)。部分 II 期溃疡患者(20 人)接受了含有微粒化银的先进敷料治疗,结果溃疡退缩至 I 期。对于不具备应用此类治疗的有利适应症的患者,则使用索法根乳膏进行治疗(60 名患者),尽管如此,还是防止了压疮阶段的恶化。I 期溃疡患者(41 人)每天使用磺胺嘧啶银喷雾剂进行治疗,这仍然有助于预防因活动不便而引起的继发性病变。在有尊严的护理时间内,尤其是在降低公司成本的情况下,卧床不起或临终病人的压疮管理目标已完全实现。最后,考虑到敷料和特定药物的当前价格,我们节省了 35% 以上的经济成本,这突出说明了在不同的方面和情况下,在尊重治疗适当性和病人依从性的同时,如何能够实施重要而简单的护理方法。
{"title":"Pharmacoeconomics and wound care. When therapeutic appropiateness and cost savings move in the same direction","authors":"I. Filoso, Ivana Citro, M. R. Iacolare, Ida Monti, Nunzio Quinto, Giacomo Russo, Attilio Tortora, Lucio Marcello Falconio","doi":"10.36017/jahc202462311","DOIUrl":"https://doi.org/10.36017/jahc202462311","url":null,"abstract":"In the year 2019, 121 patients were admitted to the Casavatore Hospice. All patients, upon admission, exhibited pressure ulcers (Ldp) in both stages I and II. A portion of the patients with stage II ulcers were treated with advanced dressings containing micronized silver (20 patients), resulting in a regression of the ulcer to stage I. Subsequently, they were treated with topical application of silver sulfadiazine cream until complete healing of the lesion. Patients who did not have favorable indications for the application of such treatment were treated with Sofargen cream (60 patients), nonetheless preventing the worsening of the stage of the pressure ulcer. Patients with stage I ulcers (41 patients) were treated daily with silver sulfadiazine spray, which still contributed to the prevention of secondary lesions associated with immobility. \u0000The objective of managing pressure ulcers in bedridden or terminal patients has been fully achieved within dignified care times and, above all, with reduced company costs. \u0000As a final result, considering the current prices for both dressings and the specific drug, we achieved an economic savings exceeding 35%, highlighting how it is possible to implement, in various aspects and situations, important yet simple care approaches while respecting therapeutic appropriateness and patient compliance.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140688551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Bua, Luigi Umberto Collovà, Girolamo Verlanti
Introduction: Clinical risk management in healthcare is the set of actions to improve the quality of care and ensure patient safety. In recent years, Italy has made progress in patient safety with the sentinel event reporting system, education and training, stakeholder engagement, and examination of legal and insurance issues. Error is unavoidable but should be considered as a "source of knowledge and improvement" to prevent repetition and ensure the safety of healthcare. However, there is no "zero risk" health care area and studies on risk management in rehabilitation are rare.Methods: This study aims to analyze the presence of clinical risk in speech therapy, identifying the most common errors and possible causes. The research was conducted with a cross-sectional statistical survey, using questionnaires administered to speech therapists operating in three Italian regions (Veneto, Campania and Sicily). The study participants were both employed and self-employed speech therapists who worked in public, private, and contracted facilities.The questionnaire consisted of two sections: the first collected demographic information about the participants, while the second focused on awareness of clinical risks and the frequency of specific errors. Respondents were asked questions about their knowledge of clinical risk in speech therapy, the frequency with which certain errors occur, and other errors they felt were important to report.The survey results were collected and analyzed using Microsoft Access software and the results were analyzed to measure outcomes. The study sample consisted of 234 speech therapists.Results: The results of the data analysis collected through Microsoft Access showed that most of the respondents (between 33% and 72%) often encountered errors in their clinical practice in various areas such as clinical evaluation of the patient's main problem, outcome measurement error, speech therapy argumentation, therapy, use of aids, respect for the patient, hygienic-sanitary standards, etc.Conclusions: The study identified common errors in the clinical practice of speech therapists, including evaluation, treatment planning, and use of aids. These errors are important for the quality of care provided to patients and should be avoided through continuous education and evidence-based clinical practices. The research provides valuable information for the speech therapy community and future research should investigate the factors contributing to training gaps in clinical risk.
导言:医疗保健领域的临床风险管理是提高医疗质量和确保患者安全的一系列行动。近年来,意大利在患者安全方面取得了进展,建立了哨点事件报告系统,开展了教育和培训,让利益相关者参与进来,并对法律和保险问题进行了研究。错误是不可避免的,但应将其视为 "知识和改进的源泉",以防止重复发生并确保医疗安全。然而,医疗保健领域不存在 "零风险",有关康复风险管理的研究也很少见:本研究旨在分析言语治疗中存在的临床风险,找出最常见的错误和可能的原因。研究采用横断面统计调查法,向意大利三个大区(威尼托大区、坎帕尼亚大区和西西里大区)的言语治疗师发放调查问卷。调查问卷由两部分组成:第一部分收集参与者的人口统计信息,第二部分重点关注临床风险意识和特定错误的发生频率。受访者被问及的问题包括他们对言语治疗临床风险的认识、某些错误发生的频率以及他们认为需要报告的其他错误。调查结果使用 Microsoft Access 软件进行收集和分析,并对结果进行分析以衡量结果。研究样本包括 234 名言语治疗师:通过 Microsoft Access 收集的数据分析结果显示,大多数受访者(33% 至 72%)在临床实践中经常遇到不同方面的错误,如临床评估患者主要问题、结果测量误差、言语治疗论证、治疗、辅助工具使用、尊重患者、卫生标准等:研究发现了言语治疗师临床实践中常见的错误,包括评估、治疗计划和辅助工具的使用。这些错误对患者的护理质量非常重要,应通过持续教育和循证临床实践加以避免。这项研究为言语治疗界提供了有价值的信息,未来的研究应调查造成临床风险培训差距的因素。
{"title":"Investigating Clinical Risk Awareness in Speech Therapy Practice","authors":"Alberto Bua, Luigi Umberto Collovà, Girolamo Verlanti","doi":"10.36017/jahc202462335","DOIUrl":"https://doi.org/10.36017/jahc202462335","url":null,"abstract":"Introduction: Clinical risk management in healthcare is the set of actions to improve the quality of care and ensure patient safety. In recent years, Italy has made progress in patient safety with the sentinel event reporting system, education and training, stakeholder engagement, and examination of legal and insurance issues. Error is unavoidable but should be considered as a \"source of knowledge and improvement\" to prevent repetition and ensure the safety of healthcare. However, there is no \"zero risk\" health care area and studies on risk management in rehabilitation are rare.Methods: This study aims to analyze the presence of clinical risk in speech therapy, identifying the most common errors and possible causes. The research was conducted with a cross-sectional statistical survey, using questionnaires administered to speech therapists operating in three Italian regions (Veneto, Campania and Sicily). The study participants were both employed and self-employed speech therapists who worked in public, private, and contracted facilities.The questionnaire consisted of two sections: the first collected demographic information about the participants, while the second focused on awareness of clinical risks and the frequency of specific errors. Respondents were asked questions about their knowledge of clinical risk in speech therapy, the frequency with which certain errors occur, and other errors they felt were important to report.The survey results were collected and analyzed using Microsoft Access software and the results were analyzed to measure outcomes. The study sample consisted of 234 speech therapists.Results: The results of the data analysis collected through Microsoft Access showed that most of the respondents (between 33% and 72%) often encountered errors in their clinical practice in various areas such as clinical evaluation of the patient's main problem, outcome measurement error, speech therapy argumentation, therapy, use of aids, respect for the patient, hygienic-sanitary standards, etc.Conclusions: The study identified common errors in the clinical practice of speech therapists, including evaluation, treatment planning, and use of aids. These errors are important for the quality of care provided to patients and should be avoided through continuous education and evidence-based clinical practices. The research provides valuable information for the speech therapy community and future research should investigate the factors contributing to training gaps in clinical risk.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"26 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tailoring the patient positioning in Magnetic Resonance Imaging, according to patient needs and clinical questions, is the key to successfully completing a highly diagnostic exam. This is evident in the MRI study of the shoulder in which, for clinical questions such as subacromial conflict syndrome and suspected lesions of the Rotator Cuff, is essential to obtain an accurate distension of the tendons, in order to make reporting free from doubtful or improper diagnoses. The possible arm placements for this kind of examination are: intra-rotation, extra-rotation, or neutral position. Each of them presents advantages and disadvantages that the MR radiographer must be able to assess in conjunction with the patient's conditions and the degree of cooperation. Intra-rotation is clearly the position that ensures greater comfort and stability to the patient and this results in the absence of artifacts from movement, but on the other hand it does not allow the distension of the supraspinatus tendon and the long head of the brachial biceps, it causes the overlap of supraspinatus tendon with infraspinatus one in the oblique coronal sequences, thus leading to misdiagnosis or dubious diagnosis. The arm’s neutral position is ideal for moderately collaborating patients and promotes a mild relaxation of the tendons and the absence of movement artifacts. Finally, the arm’s position in extra-rotation, obtained with variable positioning of pads under the forearm, ensures the collaboration of a substantial number of patients and tendons are well stretched and free from overlap, addressing reliable diagnoses, despite having, as the only disadvantage, a possible lower degree of cooperation of the patient.
{"title":"The patient positioning in the MR of the shoulder: advantages and disadvantages of the internal, external and neutral rotation of the arm","authors":"Calogero Curatolo, Maria Chiara Amato","doi":"10.36017/jahc202462318","DOIUrl":"https://doi.org/10.36017/jahc202462318","url":null,"abstract":"Tailoring the patient positioning in Magnetic Resonance Imaging, according to patient needs and clinical questions, is the key to successfully completing a highly diagnostic exam. This is evident in the MRI study of the shoulder in which, for clinical questions such as subacromial conflict syndrome and suspected lesions of the Rotator Cuff, is essential to obtain an accurate distension of the tendons, in order to make reporting free from doubtful or improper diagnoses. The possible arm placements for this kind of examination are: intra-rotation, extra-rotation, or neutral position. Each of them presents advantages and disadvantages that the MR radiographer must be able to assess in conjunction with the patient's conditions and the degree of cooperation. Intra-rotation is clearly the position that ensures greater comfort and stability to the patient and this results in the absence of artifacts from movement, but on the other hand it does not allow the distension of the supraspinatus tendon and the long head of the brachial biceps, it causes the overlap of supraspinatus tendon with infraspinatus one in the oblique coronal sequences, thus leading to misdiagnosis or dubious diagnosis. The arm’s neutral position is ideal for moderately collaborating patients and promotes a mild relaxation of the tendons and the absence of movement artifacts. Finally, the arm’s position in extra-rotation, obtained with variable positioning of pads under the forearm, ensures the collaboration of a substantial number of patients and tendons are well stretched and free from overlap, addressing reliable diagnoses, despite having, as the only disadvantage, a possible lower degree of cooperation of the patient.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"244 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140751167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Elia, Gaetano Ungaro, Carmine Pecoraro, Kevin Amoruso, Antonio Di Lascio, Riccardo Paglialunga, Gabriella Fiorillo
Cardiac amyloidosis is a rare and progressive condition caused by the buildup of amyloid in the heart. There are two common forms of cardiac amyloidosis: light-chain amyloidosis (AL) and transthyretin amyloidosis (ATTR). The deposition of amyloid in the extracellular matrix of the myocardium leads to heart failure over time, and if left untreated, it can even be fatal. For this reason, early diagnosis is essential for both prognosis and improving patients' quality of life. Since cardiac amyloidosis is a potentially treatable condition, early diagnosis is key to improving patient survival and quality of life. There is now compelling evidence showing that nuclear imaging plays a fundamental role in the non-invasive diagnosis of transthyretin cardiac amyloidosis. Due to its high sensitivity and specificity, radiotracer compounds that target the bones are considered sufficient for establishing the diagnosis, avoiding the need for endomyocardial biopsy. In this study, we analyzed data obtained from examinations conducted on patients referred to the Cardiology Department of the "San Giovanni di Dio e Ruggi d'Aragona" University Hospital, who presented with suspected cardiac amyloidosis. These patients underwent scintigraphy with 99mTc-HMDP (hydroxymethylenediphosphonate), using a large-field computerized gamma camera with a parallel-hole collimator and SPECT. After performing early whole-body planar acquisitions at 5 minutes and late acquisitions at 3 hours after intravenous administration of approximately 700 MBq of Tc-99m HMDP, myocardial uptake was observed. Subsequently, targeted acquisitions and SPECT tomographic studies were performed on the myocardial uptake areas. All acquired images were subsequently subjected to quantitative and qualitative analysis, allowing us to extract a large number of parameters reflecting morphological and predictive characteristics using radiomics and more or less automated analysis algorithms. This analysis enabled us to obtain quantitative information that is not apparent in a qualitative image analysis. The ability to extract hidden information from digital medical images is of particular interest as it can enhance the predictive capabilities of existing automatic segmentation algorithms. Extracting new information that was previously hidden can be utilized for automatic image segmentation.
心脏淀粉样变性是一种罕见的渐进性疾病,由心脏中的淀粉样蛋白堆积引起。心脏淀粉样变性有两种常见形式:轻链淀粉样变性(AL)和转甲状腺素淀粉样变性(ATTR)。淀粉样蛋白沉积在心肌的细胞外基质中,久而久之会导致心力衰竭,如果不及时治疗,甚至可能致命。因此,早期诊断对预后和改善患者的生活质量至关重要。由于心脏淀粉样变性是一种可以治疗的疾病,因此早期诊断是提高患者生存率和生活质量的关键。目前有令人信服的证据表明,核成像在无创诊断转甲状腺素心脏淀粉样变性方面发挥着重要作用。由于其高灵敏度和特异性,针对骨骼的放射性示踪剂化合物被认为足以确定诊断,从而避免了心内膜活检。在这项研究中,我们分析了转诊到 "San Giovanni di Dio e Ruggi d'Aragona "大学医院心脏科的疑似心脏淀粉样变性患者的检查数据。这些患者接受了99m锝-HMDP(羟基亚甲基二膦酸盐)闪烁扫描,使用的是带有平行孔准直器和SPECT的大视场计算机化伽马相机。在静脉注射约 700 MBq Tc-99m HMDP 后,分别于 5 分钟和 3 小时进行了早期全身平面采集和晚期采集,观察到了心肌摄取。随后,对心肌摄取区进行了定向采集和 SPECT 层析研究。所有获取的图像随后都进行了定量和定性分析,使我们能够利用放射组学和或多或少的自动分析算法提取大量反映形态和预测特征的参数。这种分析使我们能够获得在定性图像分析中不明显的定量信息。从数字医学影像中提取隐藏信息的能力特别令人感兴趣,因为它可以增强现有自动分割算法的预测能力。提取以前隐藏的新信息可用于自动图像分割。
{"title":"Use of Bone Scintigraphy in The Diagnosis of Cardiac Amyloidosis","authors":"Francesca Elia, Gaetano Ungaro, Carmine Pecoraro, Kevin Amoruso, Antonio Di Lascio, Riccardo Paglialunga, Gabriella Fiorillo","doi":"10.36017/jahc202462231","DOIUrl":"https://doi.org/10.36017/jahc202462231","url":null,"abstract":"Cardiac amyloidosis is a rare and progressive condition caused by the buildup of amyloid in the heart. There are two common forms of cardiac amyloidosis: light-chain amyloidosis (AL) and transthyretin amyloidosis (ATTR). The deposition of amyloid in the extracellular matrix of the myocardium leads to heart failure over time, and if left untreated, it can even be fatal. For this reason, early diagnosis is essential for both prognosis and improving patients' quality of life. Since cardiac amyloidosis is a potentially treatable condition, early diagnosis is key to improving patient survival and quality of life. There is now compelling evidence showing that nuclear imaging plays a fundamental role in the non-invasive diagnosis of transthyretin cardiac amyloidosis. Due to its high sensitivity and specificity, radiotracer compounds that target the bones are considered sufficient for establishing the diagnosis, avoiding the need for endomyocardial biopsy. In this study, we analyzed data obtained from examinations conducted on patients referred to the Cardiology Department of the \"San Giovanni di Dio e Ruggi d'Aragona\" University Hospital, who presented with suspected cardiac amyloidosis. These patients underwent scintigraphy with 99mTc-HMDP (hydroxymethylenediphosphonate), using a large-field computerized gamma camera with a parallel-hole collimator and SPECT. After performing early whole-body planar acquisitions at 5 minutes and late acquisitions at 3 hours after intravenous administration of approximately 700 MBq of Tc-99m HMDP, myocardial uptake was observed. Subsequently, targeted acquisitions and SPECT tomographic studies were performed on the myocardial uptake areas. All acquired images were subsequently subjected to quantitative and qualitative analysis, allowing us to extract a large number of parameters reflecting morphological and predictive characteristics using radiomics and more or less automated analysis algorithms. This analysis enabled us to obtain quantitative information that is not apparent in a qualitative image analysis. The ability to extract hidden information from digital medical images is of particular interest as it can enhance the predictive capabilities of existing automatic segmentation algorithms. Extracting new information that was previously hidden can be utilized for automatic image segmentation.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"21 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140374822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the general population of 5-year-old children, those with Specific Language Disorders represent about 7%. The difficulties, which are more evident in the first years of life, often continue into school age, for this reason, it is of crucial importance to promptly intercept these health needs to guarantee the management and resolution of linguistic difficulties which, if not treated, will transition to the area of school learning. This work aims to identify children at risk concerning language development. The screening program involved all classes of nursery school and the first and second year of primary school, evaluating possible linguistic problems in the 6-8 age group. The speech therapy screening involved the administration of the Articulation Test. From the analysis of the data, it emerged that 12% of the participants, i.e. 21 children (11 children resident in the municipality of Lampedusa and Linosa, 10 children resident in the municipality of Ustica) were identified as at risk for language delay. For children identified at risk, an in-depth clinical-diagnostic investigation was requested. From this experience of prevention and awareness at an early age for language disorders, the importance of identifying risky situations early on is evident to support the correct evolution of verbal production and avoid that a late intervention could make the most serious situation. Nursery school represents a crucial place and moment for recognizing a possible difficulty. Unfortunately, attention to children's language is not yet optimal and is often directed only to those cases that show obvious signs of delay. This is why early identification of difficulties and timely management by the speech therapist is so important.
{"title":"Speech therapy screening project in the islands of Lampedusa, Linosa and Ustica","authors":"Federico La Tona, Alberto Bua","doi":"10.36017/jahc202461317","DOIUrl":"https://doi.org/10.36017/jahc202461317","url":null,"abstract":"In the general population of 5-year-old children, those with Specific Language Disorders represent about 7%. The difficulties, which are more evident in the first years of life, often continue into school age, for this reason, it is of crucial importance to promptly intercept these health needs to guarantee the management and resolution of linguistic difficulties which, if not treated, will transition to the area of school learning. This work aims to identify children at risk concerning language development. The screening program involved all classes of nursery school and the first and second year of primary school, evaluating possible linguistic problems in the 6-8 age group. The speech therapy screening involved the administration of the Articulation Test. From the analysis of the data, it emerged that 12% of the participants, i.e. 21 children (11 children resident in the municipality of Lampedusa and Linosa, 10 children resident in the municipality of Ustica) were identified as at risk for language delay. For children identified at risk, an in-depth clinical-diagnostic investigation was requested. From this experience of prevention and awareness at an early age for language disorders, the importance of identifying risky situations early on is evident to support the correct evolution of verbal production and avoid that a late intervention could make the most serious situation. Nursery school represents a crucial place and moment for recognizing a possible difficulty. Unfortunately, attention to children's language is not yet optimal and is often directed only to those cases that show obvious signs of delay. This is why early identification of difficulties and timely management by the speech therapist is so important.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"106 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140228355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study aimed to automate CT organ segmentation using image processing and machine learning. The process involved data acquisition, labeling, neural network training, validation, testing, segmentation, analysis, interpretation, feedback, improvement, documentation, and sharing. Analyzing 20 anonymized patients on two high-performance workstations, segmenting thoraco-abdominal regions, liver, and spleen using 3D SLICER and plugins. Repeatability tests using "Autodesk Meshmixer" and "Prusa Slicer" revealed workstation 2 took nearly three times longer in 'fast' mode and 13 times longer in 'normal' mode compared to workstation 1. In conclusion, the study explored AI for organ segmentation, showing efficiency and potential cost reduction. Legal, ethical, and technical challenges include privacy concerns, professional responsibility, and the need for annotated data. Interoperability, adaptability, staff training, and continuous monitoring are crucial for AI effectiveness and safety in clinical settings. Despite challenges, AI proves valuable for precise, timely medicine, supporting medical personnel.
{"title":"Study on the adoption of an artificial intelligence algorithm for the automatic segmentation of visceral organs.","authors":"Alberto Mastrodonato, Maria Urbano","doi":"10.36017/jahc202461282","DOIUrl":"https://doi.org/10.36017/jahc202461282","url":null,"abstract":"The study aimed to automate CT organ segmentation using image processing and machine learning. The process involved data acquisition, labeling, neural network training, validation, testing, segmentation, analysis, interpretation, feedback, improvement, documentation, and sharing. Analyzing 20 anonymized patients on two high-performance workstations, segmenting thoraco-abdominal regions, liver, and spleen using 3D SLICER and plugins. Repeatability tests using \"Autodesk Meshmixer\" and \"Prusa Slicer\" revealed workstation 2 took nearly three times longer in 'fast' mode and 13 times longer in 'normal' mode compared to workstation 1. In conclusion, the study explored AI for organ segmentation, showing efficiency and potential cost reduction. Legal, ethical, and technical challenges include privacy concerns, professional responsibility, and the need for annotated data. Interoperability, adaptability, staff training, and continuous monitoring are crucial for AI effectiveness and safety in clinical settings. Despite challenges, AI proves valuable for precise, timely medicine, supporting medical personnel.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"46 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140267618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
INTRODUCTION: The COVID-19 pandemic has had a profound impact on a global scale, affecting various aspects of society, health, and well-being. It has strained healthcare systems and led to social and welfare repercussions. In the context of post-acute COVID-19 rehabilitation, there is a need to explore effective interventions for individuals, particularly those with chronic respiratory insufficiency. This study aims to evaluate the effectiveness of exercise reconditioning as a rehabilitation strategy in this specific population METHODS: A retrospective observational study was conducted at the Rehabilitation Unit in an Italian hospital between March 2020 and May 2022. The study included individuals who had been diagnosed with COVID-19 pneumonia, required hospitalization in the COVID-19 unit or intensive care unit (ICU) due to severe respiratory failure and with “post-COVID pathology syndrome” (PCS) picture. Various assessments, including the 6 Minutes Walking Test (6MWT), were conducted to determine exercise capacity. A personalized reconditioning program based on international guidelines was designed for each patient, focusing on aerobic training. Measurements of vital signs were taken during training sessions. RESULTS: A total of 24 individuals, with a mean age of 65.41 years, were included in the study. The average duration of hospitalization in the rehabilitation department was 53.17 days. Most participants had pre-existing respiratory and non-respiratory pathologies. All individuals developed COVID-19 interstitial pneumonia, and some required intensive interventions such as intubation or ECMO support. Pulmonary fibrosis and Critical Illness Myopathy (CIM) were observed in a significant portion of the participants. Significant improvements were observed in the 6MWT distance traveled, Functional Independence Measure (FIM) scale score, fraction of inhaled oxygen (FiO2), and dyspnea scores. Perceived exerction measures also showed positive changes. DISCUSSION AND CONCLUSION: The findings of this study indicate that personalized reconditioning plan is effective in improving the functional capacity and overall condition and quality of life of individuals with post-COVID pathology syndrome. These findings highlight the importance of an interdisciplinary approach and tailored rehabilitation programs in this population. Further research is needed to explore the long-term effects of exercise reconditioning in this population.
{"title":"Exercise reconditioning in the post-acute phase of COVID-19 rehabilitation in patients with chronic respiratory insufficiency: a retrospective observational study","authors":"Mariapina Rasi, Francesca Rubino, Gianluca Battaglia, Carmela Bonomo, Concetta Sorce, Giuseppe Enea","doi":"10.36017/jahc202461273","DOIUrl":"https://doi.org/10.36017/jahc202461273","url":null,"abstract":"INTRODUCTION: The COVID-19 pandemic has had a profound impact on a global scale, affecting various aspects of society, health, and well-being. It has strained healthcare systems and led to social and welfare repercussions. In the context of post-acute COVID-19 rehabilitation, there is a need to explore effective interventions for individuals, particularly those with chronic respiratory insufficiency. This study aims to evaluate the effectiveness of exercise reconditioning as a rehabilitation strategy in this specific population\u0000METHODS: A retrospective observational study was conducted at the Rehabilitation Unit in an Italian hospital between March 2020 and May 2022. The study included individuals who had been diagnosed with COVID-19 pneumonia, required hospitalization in the COVID-19 unit or intensive care unit (ICU) due to severe respiratory failure and with “post-COVID pathology syndrome” (PCS) picture. Various assessments, including the 6 Minutes Walking Test (6MWT), were conducted to determine exercise capacity. A personalized reconditioning program based on international guidelines was designed for each patient, focusing on aerobic training. Measurements of vital signs were taken during training sessions.\u0000RESULTS: A total of 24 individuals, with a mean age of 65.41 years, were included in the study. The average duration of hospitalization in the rehabilitation department was 53.17 days. Most participants had pre-existing respiratory and non-respiratory pathologies. All individuals developed COVID-19 interstitial pneumonia, and some required intensive interventions such as intubation or ECMO support. Pulmonary fibrosis and Critical Illness Myopathy (CIM) were observed in a significant portion of the participants. Significant improvements were observed in the 6MWT distance traveled, Functional Independence Measure (FIM) scale score, fraction of inhaled oxygen (FiO2), and dyspnea scores. Perceived exerction measures also showed positive changes.\u0000DISCUSSION AND CONCLUSION: The findings of this study indicate that personalized reconditioning plan is effective in improving the functional capacity and overall condition and quality of life of individuals with post-COVID pathology syndrome. These findings highlight the importance of an interdisciplinary approach and tailored rehabilitation programs in this population. Further research is needed to explore the long-term effects of exercise reconditioning in this population.\u0000 ","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140445013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Currently the conservative approach regarding shoulder instability in volleyball player results still be highly contested and discussed in clinical practice. To stipulate a rehabilitation treatment appropriate and personalized, it will be crucial to include the local region in the preliminary assessment compromised and the global kinetic chain, given the numerous correlations between the different body districts. Objective: Evaluate through the collection of literature the best scientific evidence regarding the evaluation and conservative treatment of shoulder instability in volleyball player to be used as an option in situations where surgical treatment would be excessive and invasive for the young athlete. Method: The research was conducted by a single operator through a review of the literature of the last 15 years in databases such as Medline, PubMed and Pedro. The research began in January 2022 and ended in March 2022. The selection of the articles was made on the basis of the reading of the title, abstract and full-text. Result: The research initially yielded 66 scientific articles but after reading the title, abstract and full-text, 19 related articles were considered. The best evidence has been sought regarding treatment protocols for shoulder instability in the athlete. Conclusion: According to the researches carried out the recommendations of the authors and the results obtained by the latter, the conservative approach plays a fundamental role in the recovery in case of shoulder instability. Most athletes have felt positive not only physically but also mentally. Despite this, more extensive studies will be needed in the future, to ensure the professional and the athlete a protocol of conservative recovery as appropriate as possible.
{"title":"Evaluation and conservative treatment of shoulder instability in volleyball players an overview","authors":"Luca Collebrusco, Valentina Tanoni","doi":"10.36017/jahc2024612","DOIUrl":"https://doi.org/10.36017/jahc2024612","url":null,"abstract":"Background: Currently the conservative approach regarding shoulder instability in volleyball player results still be highly contested and discussed in clinical practice. To stipulate a rehabilitation treatment appropriate and personalized, it will be crucial to include the local region in the preliminary assessment compromised and the global kinetic chain, given the numerous correlations between the different body districts.\u0000Objective: Evaluate through the collection of literature the best scientific evidence regarding the evaluation and conservative treatment of shoulder instability in volleyball player to be used as an option in situations where surgical treatment would be excessive and invasive for the young athlete.\u0000Method: The research was conducted by a single operator through a review of the literature of the last 15 years in databases such as Medline, PubMed and Pedro. The research began in January 2022 and ended in March 2022. The selection of the articles was made on the basis of the reading of the title, abstract and full-text.\u0000Result: The research initially yielded 66 scientific articles but after reading the title, abstract and full-text, 19 related articles were considered. The best evidence has been sought regarding treatment protocols for shoulder instability in the athlete.\u0000Conclusion: According to the researches carried out the recommendations of the authors and the results obtained by the latter, the conservative approach plays a fundamental role in the recovery in case of shoulder instability. Most athletes have felt positive not only physically but also mentally. Despite this, more extensive studies will be needed in the future, to ensure the professional and the athlete a protocol of conservative recovery as appropriate as possible.","PeriodicalId":14873,"journal":{"name":"Journal of Advanced Health Care","volume":"234 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140459787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}