M. Miura, Tadao Saito, H. Kitazawa, T. Itoh, T. Inamoto
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引用次数: 5
Abstract
Bovine colostrum immediately after parturition contains a high concentration ofimmunoglobulin (Ig) in which 95% or more are IgG type1} and it is important for the bovine neonate to establish passive immunity. It is also known that bovine colostrum contains various biologically active components. However, components that affect the growth of the cells involved in the immunesystem are not known. It is known that Concanavalin A (Con A) from jack beans (Canavalia ensiformis) agglutinates erythrocytes of various animal species2) and has mitogenic activity for mouse T lymphocytes.3) Con A has been isolated by a single affinity chromatography on Sephadex gel.4) In 1983, Shimada et al.5) have reported the specific binding of a part ofIg in bovine plasma to Sephadex. From the similar properties of Con A and bovine serum Ig with respect to binding to Sephadex, we suspected that certain bovine
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