Pengaruh Konsentrasi Asam Stearat Terhadap Mutu Fisik Losion Ekstrak Daun Nangka (Arthocarpus heterophyllus) Sebagai Antioksidan

Natasya Sava Agasta, Siti Aisiyah, M. Rahayu
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Abstract

Jackfruit leaf extract was developed into a lotion preparation to increase skin moisture and prevent the skin from being exposed to free radicals.  The purpose of this study was to determine the effect of variations in stearic acid base on physical quality, differences in antioxidant activity in jackfruit leaf extract and preparations, best formula that can provide antioxidant activity.Jackfruit leaf extract was obtained by maceration using 70% ethanol and then formulated with a concentration of 6% jackfruit leaf extract and variations in stearic acid base 2%, 3%, and 4%. This study used the DPPH method to determine antioxidant activity and ANOVA for statistical analysis.  This study obtained the IC50 value of jackfruit leaf extract of 64.5616 ppm. Variations of stearic acid have an effect on the physical quality and value of antioxidant activity. The IC50 value of jackfruit leaf extract and lotion was different due to the presence of additional ingredients in the lotion.  The best formula from this research, formula has the best physical quality value, with the IC50 value of the extract in the formula 70.6862 ppm and the IC50 value of the base in the formula 1179.3357 ppm. 
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草甘膦酸浓度对抗氧化剂洋甘菊提取物的生理质量的影响
菠萝蜜叶提取物被开发成一种乳液制剂,以增加皮肤水分,防止皮肤暴露于自由基。本研究旨在确定硬脂酸碱的变化对菠萝蜜叶提取物和制剂的物理品质的影响、抗氧化活性的差异,并确定能提供抗氧化活性的最佳配方。用70%乙醇浸渍得到菠萝蜜叶提取物,然后以浓度6%的菠萝蜜叶提取物和硬脂酸碱2%、3%和4%的变化配制。本研究采用DPPH法测定其抗氧化活性,并用方差分析进行统计分析。本研究得到菠萝蜜叶提取物的IC50值为64.5616 ppm。硬脂酸的变化会影响其物理品质和抗氧化活性值。菠萝蜜叶提取物和洗剂的IC50值因洗剂中添加其他成分而不同。本研究得出的最佳配方,配方具有最佳的物理品质值,萃取物在配方中的IC50值为70.6862 ppm,碱在配方中的IC50值为1179.3357 ppm。
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