{"title":"A case report of transplanted pancreas survival longer than 18 years after simultaneous pancreas-kidney transplantation and literature review","authors":"Xia Lu, N. Gong, F. Zeng, Z. Chen, Zhishui Chen","doi":"10.3760/CMA.J.ISSN.0254-1785.2019.05.005","DOIUrl":null,"url":null,"abstract":"Objective \nTo explore the influencing factors and treatment strategies of long-term survival after simultaneous pancreas and kidney transplantation (SPK). \n \n \nMethods \nOne case of long-term post-SPK survival was reviewed and its influencing factors were analyzed along with the relevant literature. \n \n \nResults \nAt 10 years post-SPK, the patient lost transplanted kidney due to rejection and underwent secondary kidney transplantation. The transplanted pancreas functioned well and has survived for more than 18 years. \n \n \nConclusions \nStrict preoperative screening, adopting mature surgical approaches, aggressive managements of various perioperative complications, strengthening of health education of recipients, improving of compliance and long-term regular follow-ups are conducive for enhancing long-term survival of recipients and grafts of SPK. \n \n \nKey words: \nSimultaneous pancreas and kidney transplantation; Diabetic nephropathy; Rejection; Regular follow-up","PeriodicalId":9885,"journal":{"name":"Chineae Journal of Organ Transplantation","volume":"20 1","pages":"277-279"},"PeriodicalIF":0.0000,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chineae Journal of Organ Transplantation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.0254-1785.2019.05.005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Objective
To explore the influencing factors and treatment strategies of long-term survival after simultaneous pancreas and kidney transplantation (SPK).
Methods
One case of long-term post-SPK survival was reviewed and its influencing factors were analyzed along with the relevant literature.
Results
At 10 years post-SPK, the patient lost transplanted kidney due to rejection and underwent secondary kidney transplantation. The transplanted pancreas functioned well and has survived for more than 18 years.
Conclusions
Strict preoperative screening, adopting mature surgical approaches, aggressive managements of various perioperative complications, strengthening of health education of recipients, improving of compliance and long-term regular follow-ups are conducive for enhancing long-term survival of recipients and grafts of SPK.
Key words:
Simultaneous pancreas and kidney transplantation; Diabetic nephropathy; Rejection; Regular follow-up
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