Overall review on analytical method development and validation of Dasatinib

Mohana Vamsi Nuli, Vijay Kumar Rekulapally
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Abstract

In this review article determines the different analytical methods for the quantitative establishment of Dasatinib by using HPLC, HPLCMS, HPLC-UV, LC-MS/MS. Pharmaceutical analytical method development of Dasatinib requires valid analytical procedures for quantitative and qualitative analysis in Pharmaceuticals dosage formulations and human serum. This assessment explains that the superiority of the HPLC/LC-MS methods reviewed is based on the quantitative analysis of drugs in formulations, (API), biological fluids such as serum and plasma.
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达沙替尼分析方法发展及验证综述
本文确定了HPLC、HPLCMS、HPLC- uv、LC-MS/MS等分析方法建立达沙替尼的定量分析方法。达沙替尼的药物分析方法的发展需要有效的分析方法来定量和定性分析药物剂量配方和人血清。这一评价说明,所审查的HPLC/LC-MS方法的优越性是基于对制剂中的药物(原料药)、血清和血浆等生物液体的定量分析。
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