Review article on endocrine diseases during pregnancy

R. R. C. Vaddadi, Tushara Bammidi, Simhavalli. Godavarthi, Swathi Priya Vana, Jagadish Chandra Prasad Teddu
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Abstract

Pregnancy is the period where a woman undergoes several physical and hormonal changes in accordance to the growth of the fetus. Wide alteration in the levels of hormones from the normal values affect the state of gestation and the growth of the baby. Especially the most commonly encountered disorders like pregnancy induced thyroid disorder effects the neuro development of the baby whereas gestational diabetes makes mode of delivery complex. Hormonal imbalance can be investigated by haematological findings like thyroid stimulating hormone (TSH), T3 and T4 tests to identify thyroid disorders whereas HbA1C, Random blood sugar(RBS), fasting random blood sugar(FRBS) , post prandial blood sugar (PPBS) and oral glucose tolerance test (OGTT) to screen gestational diabetes. Apart form these there are some uncommon hormonal pregnancy disorders like cushing syndrome, conns syndrome, congenital adrenal hyperplasia, adrenal insufficiency. These complexes can be rectified up to certain extent by diagnosing them before hand thereby implementing life style changes, dietary changes and taking medications. Therefore, prior screening of the diseases is important in supress further complications in pregnancy and to have healthy progeny.
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妊娠期内分泌疾病综述
怀孕期间,妇女的身体和荷尔蒙会随着胎儿的生长而发生变化。激素水平从正常值的广泛改变影响妊娠状态和婴儿的生长。特别是最常见的妊娠性甲状腺疾病影响了婴儿的神经发育,而妊娠糖尿病使分娩方式复杂化。激素失衡可通过血液学检查进行调查,如促甲状腺激素(TSH)、T3和T4测试,以确定甲状腺疾病,而HbA1C、随机血糖(RBS)、空腹随机血糖(FRBS)、餐后血糖(PPBS)和口服葡萄糖耐量试验(OGTT)可筛查妊娠糖尿病。除此之外,还有一些罕见的激素妊娠障碍,如库欣综合征,康斯综合征,先天性肾上腺增生,肾上腺功能不全。通过提前诊断,从而改变生活方式,改变饮食习惯和服用药物,可以在一定程度上纠正这些并发症。因此,事先筛查这些疾病对于抑制妊娠期进一步的并发症和拥有健康的后代是重要的。
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