Alpha-fetoprotein (AFP) in Gynecological Tumors

P. Ouyang, Su‐cheng Huang, F. Hsieh, Ann‐Jan Pang, H. Wen, P. Wei
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Abstract

AFP in 262 patients with genital malignancy, 28 with non-genital malignancy, 58 with benign ovarian tumors, 56 with hydatidiform mole, 12 with choriocarcinoma and 83 healthy females was determined by AFP radioimmunoassay. It was found in 1 patient with corpus cancer, 5 with ovarian malignancy, 4 with testicular malignancy and 2 with partial hydatidiform mole. The importance of immunocytochemical localization of tumor markers is emphasized and the concept of apparent half-life (AHL) of AFP is introduced.
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甲胎蛋白在妇科肿瘤中的作用
用AFP放射免疫法测定262例生殖器官恶性肿瘤患者、28例非生殖器官恶性肿瘤患者、58例卵巢良性肿瘤患者、56例包虫痣患者、12例绒毛膜癌患者和83例健康女性患者的AFP水平。其中1例为体癌,5例为卵巢恶性肿瘤,4例为睾丸恶性肿瘤,2例为部分葡萄胎。强调了肿瘤标志物免疫细胞化学定位的重要性,并介绍了AFP的表观半衰期(AHL)概念。
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