Mycoplasmosis: experimental pyelonephritis in rats; Demonstration of antibody in urine and serum.

S. Rosendal, Thomsen Ac
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引用次数: 1

Abstract

The concentration and persistence of M. arthritidis in obstructed and unobstructed kidneys of rats after intracardial inoculation has been investigated. Inoculation of 108 c.f.u. M. arthritidis, giving a deposit of 104 c.f.u./g kidney tissue, depressed the resistance against E. coli so that secondary intravenous inoculation of 106 or 107 of E. coli would be followed by severe acute pyelonephritis. These doses of E. coli could not provoke inflammation if given without primary mycoplasma inoculation.
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支原体病:实验性大鼠肾盂肾炎尿和血清中抗体的证明。
研究了心内接种大鼠梗阻和未梗阻肾脏中关节炎支原体的浓度和持续性。接种108 c.f.u.的关节炎分枝杆菌,使肾组织沉积104 c.f.u./g,降低了对大肠杆菌的抵抗力,因此继发静脉接种106或107个大肠杆菌会导致严重的急性肾盂肾炎。如果不接种原支原体,这些剂量的大肠杆菌不会引起炎症。
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