Structure and Function of Eukaryotic DNA-Binding Proteins in DNA Repair

S. J. Kind, M. Sanderson
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Abstract

This article reviews the current status of how structural studies are impacting on our understanding of the mechanism of Eukaryotic repair from a function standpoint. A wide array of different repair mechanisms are covered, namely DNA base excision repair (BER), nucleotide excision repair (NER) and mismatch repair (MMR)
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真核生物DNA结合蛋白在DNA修复中的结构与功能
本文综述了结构研究如何从功能角度影响我们对真核细胞修复机制的理解的现状。它涵盖了一系列不同的修复机制,即DNA碱基切除修复(BER)、核苷酸切除修复(NER)和错配修复(MMR)。
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