Effects of Catholyte Water on the Development of Experimental Graffi Tumor on Hamsters

Central European Journal of Medicine Pub Date : 2019-03-05 DOI:10.13187/ejm.2019.1.45

I. Ignatov, Christos Drossinakis, R. Toshkova, E. Zvetkova

{"title":"Effects of Catholyte Water on the Development of Experimental Graffi Tumor on Hamsters","authors":"I. Ignatov, Christos Drossinakis, R. Toshkova, E. Zvetkova","doi":"10.13187/ejm.2019.1.45","DOIUrl":null,"url":null,"abstract":"The paper describes the results of a pilot study aimed at the investigation of the influence of catholyte (electrolyzed\nalkaline water) on the development of tumors. In the experiments solid Graffi tumor was transplanted subcutaneously in\nthe back of the experimental group of Golden Syrian hamsters. Tumor appearance and growth were registered every day.\nBlood parameters were measured on the 10th and 25th day after transplantation and blood smears were prepared.\nHamsters treated with catholyte developed tumor with some delay compared to untreated (drinking tap water) ones.\nAlso, the tumor growth was slow and the survival rate was increased. The analysis of blood parameters and cell\nmorphology has shown significant differences in the value of some hematometric parameters and morphological changes\nof some blood cells. The obtained results suggest about the beneficial influence of catholyte and the possible use of it as a\nsupporting non-invasive therapy of cancer diseases.\nKeywords: ORP: Oxidation Reduction Potential; AST: Average Survival Time; WBCs/LR: White Blood Cells to\nLymphocyte Ratio; NLR: Neutrophil to Lymphocyte Ratio; TILs: Tumor-Infiltration Cells","PeriodicalId":50709,"journal":{"name":"Central European Journal of Medicine","volume":"29 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"14","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Central European Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13187/ejm.2019.1.45","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 14

Abstract

The paper describes the results of a pilot study aimed at the investigation of the influence of catholyte (electrolyzed alkaline water) on the development of tumors. In the experiments solid Graffi tumor was transplanted subcutaneously in the back of the experimental group of Golden Syrian hamsters. Tumor appearance and growth were registered every day. Blood parameters were measured on the 10th and 25th day after transplantation and blood smears were prepared. Hamsters treated with catholyte developed tumor with some delay compared to untreated (drinking tap water) ones. Also, the tumor growth was slow and the survival rate was increased. The analysis of blood parameters and cell morphology has shown significant differences in the value of some hematometric parameters and morphological changes of some blood cells. The obtained results suggest about the beneficial influence of catholyte and the possible use of it as a supporting non-invasive therapy of cancer diseases. Keywords: ORP: Oxidation Reduction Potential; AST: Average Survival Time; WBCs/LR: White Blood Cells to Lymphocyte Ratio; NLR: Neutrophil to Lymphocyte Ratio; TILs: Tumor-Infiltration Cells

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Catholyte Water对仓鼠实验性涂鸦瘤发展的影响

本文介绍了一项旨在探讨阴极电解质(电解碱性水)对肿瘤发展影响的初步研究结果。实验中，在实验组金叙利亚仓鼠背部皮下移植实体格菲瘤。每天记录肿瘤外观及生长情况。于移植后第10天和第25天测定血液参数，并制作血涂片。与未接受治疗(饮用自来水)的仓鼠相比，接受阴极电解质治疗的仓鼠出现肿瘤的时间有所延迟。肿瘤生长缓慢，生存率提高。血液参数和细胞形态学的分析表明，一些血液参数的值和一些血细胞的形态学变化有显著差异。所获得的结果提示了catholyte的有益影响，并可能将其用于支持癌症疾病的非侵入性治疗。关键词:ORP;氧化还原电位;AST:平均生存时间;白细胞/淋巴细胞比率;NLR:中性粒细胞与淋巴细胞比值;til:肿瘤浸润细胞

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Central European Journal of Medicine 医学-医学：内科

自引率

0.00%

发文量

审稿时长

4-8 weeks