{"title":"Pay attention to the etiological analysis and management of 2019 coronavirus disease associated liver injury","authors":"Ling Yang, Weifen Xie","doi":"10.3760/CMA.J.CN311367-20200317-00152","DOIUrl":null,"url":null,"abstract":"2019 coronavirus disease(COVID-19) as a novel infectious respiratory disease, has become pandemic worldwide. The clinical manifestation of COVID-19 is complicated and varied. In addition to lung injury, liver is also one of the important organs to be affected. Abnormal liver function is common in the various stage of COVID-19. It is urgent to pay attention to the role of hypoxic-ischemia-reperfusion injury and drug-induced liver injury. Careful differentiation and precise management of COVID-19 associated liver injury are critical to reduce the incidence rate, improve the survival rate and shorten hospital stays. In the future to strengthen the pathophysiologic, therapeutic and prognostic research of COVID-19 associated liver injury is also required. \n \nKey words: \n2019 coronavirus disease; Liver injury; Hepatic hypoxic-ischemia-reperfusion injury; Drug-induced liver injury","PeriodicalId":10009,"journal":{"name":"中华消化杂志","volume":"10 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华消化杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.CN311367-20200317-00152","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
2019 coronavirus disease(COVID-19) as a novel infectious respiratory disease, has become pandemic worldwide. The clinical manifestation of COVID-19 is complicated and varied. In addition to lung injury, liver is also one of the important organs to be affected. Abnormal liver function is common in the various stage of COVID-19. It is urgent to pay attention to the role of hypoxic-ischemia-reperfusion injury and drug-induced liver injury. Careful differentiation and precise management of COVID-19 associated liver injury are critical to reduce the incidence rate, improve the survival rate and shorten hospital stays. In the future to strengthen the pathophysiologic, therapeutic and prognostic research of COVID-19 associated liver injury is also required.
Key words:
2019 coronavirus disease; Liver injury; Hepatic hypoxic-ischemia-reperfusion injury; Drug-induced liver injury
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