{"title":"Synthesis and Characterization of N-Substituted Tetrahydroiso-quinoline Derivatives via a Pictet-Spengler Condensation","authors":"Heta A. Patel, Arun L. Patel","doi":"10.6000/1929-5030.2014.03.03.5","DOIUrl":null,"url":null,"abstract":"Synthesis of N-substituted 1,2,3,4 –tetrahydroisoquinoline derivatives and bis-isoquinoline has been carried out via a Pictet-Spengler condensation. Tetrahydroisoquinolines were obtained from 2-(3’,4’-dimethoxyphenyl) ethylamine in four steps. The entire synthesized compounds were characterized by IR, 1 H NMR and mass spectral data.","PeriodicalId":15165,"journal":{"name":"Journal of Applied Solution Chemistry and Modeling","volume":"51 1","pages":"169-174"},"PeriodicalIF":0.0000,"publicationDate":"2014-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Solution Chemistry and Modeling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6000/1929-5030.2014.03.03.5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Synthesis of N-substituted 1,2,3,4 –tetrahydroisoquinoline derivatives and bis-isoquinoline has been carried out via a Pictet-Spengler condensation. Tetrahydroisoquinolines were obtained from 2-(3’,4’-dimethoxyphenyl) ethylamine in four steps. The entire synthesized compounds were characterized by IR, 1 H NMR and mass spectral data.
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