Peut-on prévenir la survenue de douleurs chroniques dans la polyarthrite rhumatoïde ?

Abstract

Although the prognosis of rheumatoid arthritis (RA) has been revolutionised by the advent of targeted disease-modifying anti-rheumatic drugs, chronic pain persists in many RA patients. While some of this pain is related to failure of the current therapies to control inflammation, a large majority is non-inflammatory refractory pain. Understanding, managing and preventing this pain remains a major challenge. In this narrative review, we will first present the risk factors associated with their occurrence and the mechanisms involved. We will then discuss the prevention strategies that can be put in place today.