{"title":"Simulating tumour vasculature at multiple scales","authors":"J. Grogan, P. Maini, J. Pitt-Francis, H. Byrne","doi":"10.1109/IARWISOCI.2014.7034633","DOIUrl":null,"url":null,"abstract":"The vasculature plays an important role in tumour development and treatment, acting as a conduit for nutrients, waste products and therapeutics. Simulating transport and network structure evolution in malformed tumour networks is a challenging multi-scale problem. Current approaches for modelling the vasculature at distinct size scales are described here, followed by a discussion of current efforts in developing integrated multi-scale modelling approaches for simulating the growth and treatment of vascular tumours.","PeriodicalId":93358,"journal":{"name":"Proceedings of the 2014 6th International Advanced Research Workshop on In Silico Oncology and Cancer Investigation : the CHIC Project Workshop (IARWISOCI) : Athens, Greece, 3-4 November 2014. International Advanced Research Workshop on...","volume":"286 1","pages":"1-4"},"PeriodicalIF":0.0000,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2014 6th International Advanced Research Workshop on In Silico Oncology and Cancer Investigation : the CHIC Project Workshop (IARWISOCI) : Athens, Greece, 3-4 November 2014. International Advanced Research Workshop on...","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IARWISOCI.2014.7034633","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

The vasculature plays an important role in tumour development and treatment, acting as a conduit for nutrients, waste products and therapeutics. Simulating transport and network structure evolution in malformed tumour networks is a challenging multi-scale problem. Current approaches for modelling the vasculature at distinct size scales are described here, followed by a discussion of current efforts in developing integrated multi-scale modelling approaches for simulating the growth and treatment of vascular tumours.
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在多个尺度上模拟肿瘤血管系统
血管系统在肿瘤的发展和治疗中起着重要的作用,作为营养物质、废物和治疗药物的管道。模拟畸形肿瘤网络中的传输和网络结构演化是一个具有挑战性的多尺度问题。本文描述了目前在不同尺寸尺度上对血管系统进行建模的方法,然后讨论了目前在开发用于模拟血管肿瘤生长和治疗的综合多尺度建模方法方面所做的努力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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