Electro-spun nano fiber of carboxymethyl cellulose – curcumin and its applications

L S Afinisha Deepam, M. Krishnan, S AswathySudhakar, S PaulrajL
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Abstract

Cellulose is a prominent scaffolding polysaccharide found in plants as micro fibrils which form the structurally strong framework in the cell walls. It has wide variety of uses such as attacking agent, emulsifier, stabilizer etc. Its use can be further enhanced by converting cellulose into cellulose derivatives. One of the most important cellulose derivatives is carboxy methyl cellulose (CMC). In the present study, cellulose is converted to CMC thereby preparing CMC – curcumin nanofiber by using electro spinning method. The functional groups identification was done by using UV Visible spectroscopy and FT-IR. Surface structure was analyzed by using Scanning Electron Microscopy. The antifungal activity was studied against Aspergillus niger and Candida albicans. . The antibacterial activities also studied for the samples against E.coli, Klebsiella pneumonia, Streptococcus mutans and Staphylococcus aureus.
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羧甲基纤维素-姜黄素电纺丝纳米纤维及其应用
纤维素是一种突出的支架多糖,在植物中以微原纤维的形式存在,形成细胞壁结构坚固的框架。它具有多种用途,如攻击剂、乳化剂、稳定剂等。通过将纤维素转化为纤维素衍生物,可以进一步增强其用途。羧甲基纤维素是一种重要的纤维素衍生物。本研究采用电纺丝法将纤维素转化为CMC,制备CMC -姜黄素纳米纤维。利用紫外可见光谱和傅里叶红外光谱对其官能团进行了鉴定。用扫描电镜对其表面结构进行了分析。研究了其对黑曲霉和白色念珠菌的抑菌活性。并研究了样品对大肠杆菌、肺炎克雷伯菌、变形链球菌和金黄色葡萄球菌的抑菌活性。
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