Antibiotic Resistance Pattern Of Pseudomonas Aeruginosa Isolated From Clinical Specimens In A Tertiary Hospital In Northeastern Nigeria

Abstract

A total of 106 greenish, pigmented consecutive non-duplicate Pseudomonas aeruginosa isolates from clinical specimens were examined. The mean age of the patients was 28.8+17.3 years, comprised of 56 (52.8%) males and 50 (47.2%) females. High prevalence of pseudomonal infections occurred more in age-group 20-29 years, 26 (24.6%) and least in 50-59years and >60years, 6 (5.7%), respectively. Majority of the isolates were recovered from wounds specimens, 42 (39%). Overall antibiotic susceptibility pattern showed that sparfloxacin demonstrated highest sensitivity of 84.9%, followed by ciprofloxacin, 69.8% and perfloxacin, 52.8%. Other results were cefuroxime, 49.1%, and ceftrazone, 13.2%. Majority of the isolates exhibited multidrug resistance pattern. In conclusion, the multidrug resistance pattern of P. aeruginosa isolates observed in this study posed a dire clinical consequence, especially in patients management with pseudomonal infections and infections control approach in hospital environment due to rapid dissemination of the strains