A. Akhter, K. Fatema, A. Afroz, B. Bhowmik, L. Ali, A. Hussain
{"title":"Prevalence of Diabetes Mellitus and its Associated Risk Indicators in a Rural Bangladeshi Population","authors":"A. Akhter, K. Fatema, A. Afroz, B. Bhowmik, L. Ali, A. Hussain","doi":"10.2174/1876524601104010006","DOIUrl":null,"url":null,"abstract":"Background: Substantial racial heterogeneity in diabetes leads to the necessity of conducting epidemiological studies in different communities. Such studies are still inadequate in Bangladeshi population, particularly in truly respective rural areas. The objectives of the study were to estimate the prevalence of diabetes and to identify its associated risk indicators in a rural population of Bangladesh. Methods: This population based cross-sectional study was conducted in remote rural areas of Northern Bangladesh, which included a total of 836 participants aged at or above 25 years through screening in camp settings. Diabetes was diagnosed by WHO criteria after a 2-sample OGTT. BMI, waist-hip ratio, blood pressure, lipid profile and serum creatinine were also estimated. Results: The prevalence of diabetes was found to be 7.2% (95% CI 5.4-9.0) and that of impaired glucose regulation (including both impaired glucose tolerance (IGT) and/or impaired fasting glucose (IFG)) was 6.5% (95% CI 4.8-8.2). The prevalence of diabetes and impaired glucose regulation differed between males and females, but, both increased with age in males as well as females. A good correlation was observed between fasting blood glucose and 2hr after glucose (Kappa value 0.86) among the study participants. After adjusting for potential confounders BMI and WHR were found as significant independent risk indicators for the occurrence of diabetes in this population.","PeriodicalId":22762,"journal":{"name":"The Open Diabetes Journal","volume":"47 1","pages":"6-13"},"PeriodicalIF":0.0000,"publicationDate":"2011-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"39","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Open Diabetes Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1876524601104010006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 39
Abstract
Background: Substantial racial heterogeneity in diabetes leads to the necessity of conducting epidemiological studies in different communities. Such studies are still inadequate in Bangladeshi population, particularly in truly respective rural areas. The objectives of the study were to estimate the prevalence of diabetes and to identify its associated risk indicators in a rural population of Bangladesh. Methods: This population based cross-sectional study was conducted in remote rural areas of Northern Bangladesh, which included a total of 836 participants aged at or above 25 years through screening in camp settings. Diabetes was diagnosed by WHO criteria after a 2-sample OGTT. BMI, waist-hip ratio, blood pressure, lipid profile and serum creatinine were also estimated. Results: The prevalence of diabetes was found to be 7.2% (95% CI 5.4-9.0) and that of impaired glucose regulation (including both impaired glucose tolerance (IGT) and/or impaired fasting glucose (IFG)) was 6.5% (95% CI 4.8-8.2). The prevalence of diabetes and impaired glucose regulation differed between males and females, but, both increased with age in males as well as females. A good correlation was observed between fasting blood glucose and 2hr after glucose (Kappa value 0.86) among the study participants. After adjusting for potential confounders BMI and WHR were found as significant independent risk indicators for the occurrence of diabetes in this population.
背景:糖尿病存在明显的种族异质性,因此有必要在不同社区开展流行病学研究。在孟加拉国人口中,特别是在真正各自的农村地区,这种研究仍然不足。该研究的目的是估计孟加拉国农村人口中糖尿病的患病率,并确定其相关风险指标。方法:这项基于人口的横断面研究是在孟加拉国北部偏远的农村地区进行的,其中包括836名年龄在25岁或以上的参与者,他们在营地环境中进行了筛查。2个样本OGTT后,根据WHO标准诊断为糖尿病。BMI、腰臀比、血压、血脂和血清肌酐也进行了评估。结果:糖尿病患病率为7.2% (95% CI 5.4-9.0),葡萄糖调节受损(包括糖耐量受损(IGT)和/或空腹血糖受损(IFG))的患病率为6.5% (95% CI 4.8-8.2)。糖尿病患病率和血糖调节障碍在男性和女性之间存在差异,但两者都随着年龄的增长而增加。在研究参与者中,空腹血糖与葡萄糖后2小时之间存在良好的相关性(Kappa值0.86)。在对潜在混杂因素进行调整后,BMI和WHR被发现是该人群发生糖尿病的重要独立风险指标。