G6PC2 rs560887 Gene Variant is Associated with Fasting Blood Glucose in the Admixed Mexican Population

Rodrigo Fernández-Pons, P. Costa-Urrutia, Jacqueline Solares-Tlapechco, J. Granados, M. E. Rodríguez-Arellano
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Abstract

In Mexico, type 2 diabetes prevalence is 13.7%, which has a huge impact on Mexican public health. There is an urgent need to focus on the prevention of pre-diabetes to decrease the likelihood of type 2 diabetes onset. Gene variants predisposed to increase Fasting Blood Glucose (FBG) and glycosylated hemoglobin (HbA1c) levels could be helpful for prevention purposes. This study aimed to analyze the association of the G6PC2 rs560887 variant with pre-diabetes in a Mexican-Mestizo population.
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G6PC2 rs560887基因变异与墨西哥混血人群空腹血糖相关
在墨西哥,2型糖尿病患病率为13.7%,这对墨西哥的公共卫生产生了巨大影响。迫切需要关注糖尿病前期的预防,以降低2型糖尿病发病的可能性。易增加空腹血糖(FBG)和糖化血红蛋白(HbA1c)水平的基因变异可能有助于预防。本研究旨在分析G6PC2 rs560887变异与墨西哥-梅斯蒂索人前驱糖尿病的关系。
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