Role Of Hypertension and Obesity as Risk Factors for Ihd

Mohammad Mujtaba Ghaffari, Abdul Samad Ahmadi, Kyat Biandivich Abzaliev, Aida Akhenbaeva, N. Glushkova
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Abstract

Background: Hypertension and obesity are two major modifiable risk factors for CAD, most of the time there will be more than two risk factors in an IHD. Obesity itself cause insulin resistance to initiate type -2 DM. is the most common and significant RFs for IHD, and proper BP management is the cornerstone of both direct and indirect prevention. Overweight and obesity account for more than 80% of CHD patients. Obesity is sometimes viewed as a "minor" CHD RF; however, it is a widely effective risk-factor approach. A range of "major" risk factors have been proven to be significantly influenced by weight loss, including HTN, hyperlipidemia and insulin resistance/T2DM. Aim: To assess arterial hypertension and obesity as risk factors of IHD. Methods: This cross-sectional study which was done retrospectively by collecting data from database of "Scientific Research Institute of Cardiology and Internal Diseases" Almaty city, Kazakhstan during 2020. IHD confirmed by history, physical exam, angiography and other lab findings. Result: The research involved a total of 649 participants. The mean age of study population was 64.2±9.24 (P = 0,000). Mean of SBP and DBP were 180.73±34.9; 99.48±14.28 mmHg respectively. Number of females with normal BMI 50(21.6%), overweight 93(40.10%), obesity class – 1, 59(25.4%), obesity class – 2, 23(9.90%) and obesity class – 3, 7(3%), (P = 0.486). Number of males with underweight BMI 1(0.20%), normal BMI 96(23%), overweight 190(45.6%), obesity class – 1, 89(21.3%), obesity class – 2, 29(7%) and obesity class – 3, 12(2.9%). (P = 0.486). The Mean BMI in both genders was (28.72±11.79). Conclusion: The burden of CVDs and their related risk factors are significant in Almaty, posing a major public health concern. For accurate management and implementation of preventive measures in this area, effective strategies in management, education, and healthcare centers are needed.
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高血压和肥胖作为Ihd危险因素的作用
背景:高血压和肥胖是冠心病的两个主要可改变的危险因素,大多数情况下IHD会有两个以上的危险因素。肥胖本身导致胰岛素抵抗引发2型糖尿病是IHD最常见和最重要的RFs,适当的血压管理是直接和间接预防的基石。超重和肥胖占冠心病患者的80%以上。肥胖有时被视为“轻微”冠心病;然而,它是一种广泛有效的风险因素方法。一系列“主要”危险因素已被证明受减肥的显著影响,包括HTN、高脂血症和胰岛素抵抗/ 2型糖尿病。目的:探讨高血压和肥胖是IHD的危险因素。方法:采用回顾性横断面研究方法,收集哈萨克斯坦阿拉木图市“心脏病与内科疾病科学研究所”数据库2020年的数据。经病史、体格检查、血管造影和其他实验室检查证实为IHD。结果:该研究共涉及649名参与者。研究人群平均年龄为64.2±9.24岁(P = 0000)。收缩压、舒张压平均值为180.73±34.9;99.48±14.28 mmHg。BMI正常50(21.6%),超重93(40.10%),肥胖1,59(25.4%),肥胖2,23(9.90%),肥胖3,7 (3%),(P = 0.486)。BMI过轻1(0.20%),BMI正常96(23%),超重190(45.6%),肥胖1.89(21.3%),肥胖2.29(7%),肥胖3.12(2.9%)。(p = 0.486)。男女平均BMI为(28.72±11.79)。结论:阿拉木图地区心血管疾病负担及其相关危险因素显著,存在重大公共卫生问题。为了准确地管理和实施这一领域的预防措施,需要在管理、教育和保健中心采取有效的战略。
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