Oxidative and inflammatory status and HDL functions of obese pre and post menopausal women

IF 0.6 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Turkish Journal of Biochemistry-turk Biyokimya Dergisi Pub Date : 2014-01-01 DOI:10.5505/TJB.2014.82787

O. Alatas, A. Akalin, G. Çiftçi, G. Yorulmaz, Ipek Ertorun, N. Kebapçı, B. Efe

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Abstract

Objective: Obesity and age related vascular changes coupled with the effect of estrogen with- drawal increases predisposition to atherosclerosis in postmenopausal women. But the func- tions of high density lipoprotein (HDL) were not well established in postmenopausal women. In the present study, we mainly aimed to evaluate the changes in the functions of HDL and aimed to measure, lipid peroxidation, lipid profile and homocysteine levels as a supporting evidence in pre and postmenopausal obese women as a result of estrogen depletion. Material and Methods: This study included 20 premenopausal, 22 postmenopausal 42 obese (BMI>30 kg/m2) and 26 premenopausal non-obese. These twenty six premenopausal women with normal BMI (20

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绝经前和绝经后肥胖妇女的氧化和炎症状态及HDL功能

目的:肥胖和年龄相关的血管改变加上雌激素的作用增加了绝经后妇女动脉粥样硬化的易感性。但在绝经后妇女中高密度脂蛋白(HDL)的功能尚未得到很好的确定。在本研究中，我们主要旨在评估HDL功能的变化，旨在测量脂质过氧化、脂质谱和同型半胱氨酸水平，作为绝经前和绝经后肥胖妇女雌激素耗竭的支持证据。材料与方法:本研究纳入20名绝经前患者，22名绝经后肥胖者(BMI>30 kg/m2)和26名绝经前非肥胖者。选取BMI正常(20

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来源期刊

Turkish Journal of Biochemistry-turk Biyokimya Dergisi 生物-生化与分子生物学

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Turkish Journal of Biochemistry (TJB), official journal of Turkish Biochemical Society, is issued electronically every 2 months. The main aim of the journal is to support the research and publishing culture by ensuring that every published manuscript has an added value and thus providing international acceptance of the “readability” of the manuscripts published in the journal.