Synthesis and Study Biological Activities of Sulfur - Containing Drugs

Zainab Saeed, M. Saleh, Ghufran T Sadeek
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Abstract

The importance of developing sulfur therapy is crucial to achieving the progress of pharmaceutical works - functional groups produced from sulfur can be found in a wide range of medicines due to the components of various biological and pharmaceutical effects. Sulfur compounds are an important class of chemical molecules. It can be used in various areas of chemistry. As a result of the widespread of pharmaceutical compounds containing sulfur, it gave great importance, as there are many drugs that have been developed, such as mafenide, sulfacetamide, Sulfadiazine, sulfamethazine, Sulfasalazine, sulfisoxazole. The study dealt with collecting the most important methods of preparing organic sulfur compounds. The focus was on thiols, thiones and sulfones, and a comparison was made between the pharmaceutical compounds that are included in their compositions in terms of synthesis and medical uses as antibacterial, antifungal and anticancer cells.
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含硫药物的合成及生物活性研究
硫疗法的发展对药学工作的进展至关重要,硫所产生的官能团由于其各种生物和药物作用的组成而广泛存在于各种药物中。含硫化合物是一类重要的化学分子。它可用于化学的各个领域。由于含有硫的药物化合物广泛存在,因此它具有很大的重要性,因为已经开发了许多药物,如马菲尼德,磺胺乙酰胺,磺胺嘧啶,磺胺乙嘧啶,磺胺嘧啶,磺胺嘧啶,磺胺恶唑。本研究收集了制备有机硫化合物的最重要方法。重点是硫醇、硫酮和砜,并就其组合物中所含的药物化合物的合成和抗菌、抗真菌和抗癌细胞的医疗用途进行了比较。
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