{"title":"Microbial Transformation of Danazol","authors":"M. Choudhary, Azizuddin, Atta-ur-rahman","doi":"10.1080/10575630290019994","DOIUrl":null,"url":null,"abstract":"Danazol (17 -hydroxy-17 -pregna-2,4-dien-20-yno-[2,3- d ] isoxazole) ( 1 ) on fermentation with Fusarium lini , Aspergillus niger , and Cephalosporium aphidicola yielded 17 -hydroxy-2-(hydroxymethyl)-17- -pregn-4-en-20-yn-3-one ( 2 ) and 17 -hydroxy-2-(hydroxymethyl)-17 -pregna-1,4-dien-20-yn-3-one ( 3 ), while the fermentation of 1 with Bacillus cerus yielded compound 2 only.","PeriodicalId":18873,"journal":{"name":"Natural Product Letters","volume":"465 1","pages":"101 - 106"},"PeriodicalIF":0.0000,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"22","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/10575630290019994","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 22
达那唑的微生物转化
Danazol(17 -羟基-17- pregna-2,4-dien-20-yno-[2,3- d]异恶唑)(1)与lini镰镰菌、黑曲霉和aphidicola头孢菌发酵产生17-羟基-2-(羟甲基)-17- -pregna- 4-en-20-yn-3-one(2)和17-羟基-2-(羟甲基)-17- pregna-1,4-dien-20-yn-3-one(3)，而与cerus芽孢杆菌发酵1只产生化合物2。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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