Carlos Lázaro Perona , Enrique Alcalde García , María Teresa Sanz-Casla , Elena Hernández Álvarez , Fiorella Medina Salazar , María Ángeles Cuadrado Cenzual
{"title":"Leucemia/linfoma de células T del adulto: a propósito de un caso","authors":"Carlos Lázaro Perona , Enrique Alcalde García , María Teresa Sanz-Casla , Elena Hernández Álvarez , Fiorella Medina Salazar , María Ángeles Cuadrado Cenzual","doi":"10.1016/j.labcli.2018.12.003","DOIUrl":null,"url":null,"abstract":"<div><p>Adult T-cell leukaemia/lymphoma is a mature peripheral T-cell leukaemia of adults associated with infection by the human retrovirus HTLV-1 that presents with highly variable systemic and cutaneous manifestations. HTLV-1 is estimated to affect at least 5-10 million people worldwide, and its geographic distribution in endemic regions is closely related to ATLL prevalence. Adult T-cell leukaemia/lymphoma is classified into different clinical types according to its clinical characteristics, with acute and lymphomatous types having the worst prognosis. Differential diagnosis of adult T-cell leukaemia/lymphoma can be difficult due to the non-specific symptoms in affected individuals. The Clinical Analysis laboratory can help initiate the diagnosis by visualising pathognomonic cells for adult T-cell leukaemia/lymphoma in a peripheral smear.</p></div>","PeriodicalId":101105,"journal":{"name":"Revista del Laboratorio Clínico","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista del Laboratorio Clínico","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1888400819300200","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Adult T-cell leukaemia/lymphoma is a mature peripheral T-cell leukaemia of adults associated with infection by the human retrovirus HTLV-1 that presents with highly variable systemic and cutaneous manifestations. HTLV-1 is estimated to affect at least 5-10 million people worldwide, and its geographic distribution in endemic regions is closely related to ATLL prevalence. Adult T-cell leukaemia/lymphoma is classified into different clinical types according to its clinical characteristics, with acute and lymphomatous types having the worst prognosis. Differential diagnosis of adult T-cell leukaemia/lymphoma can be difficult due to the non-specific symptoms in affected individuals. The Clinical Analysis laboratory can help initiate the diagnosis by visualising pathognomonic cells for adult T-cell leukaemia/lymphoma in a peripheral smear.
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